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crestin crestin [ Danio rerio (zebrafish) ]

Gene ID: 30186, updated on 9-Dec-2024

Summary

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Official Symbol
crestinprovided by ZNC
Official Full Name
crestinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-000208-13
See related
Ensembl:ENSDARG00000105570 AllianceGenome:ZFIN:ZDB-GENE-000208-13
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Is expressed in several structures, including ectomesenchyme; embryonic structure; head; nervous system; and neural crest. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See crestin in Genome Data Viewer
Location:
chromosome: 4
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (47257854..47262290)
105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (45690506..45694942)

Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene transfer RNA valine (anticodon AAC) Neighboring gene transfer RNA leucine (anticodon CAG) Neighboring gene oocyte zinc finger protein XlCOF6-like Neighboring gene uncharacterized LOC137491061

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An evolutionarily conserved mechanism of calcium-dependent neurotoxicity in a zebrafish model of fetal alcohol spectrum disorders. Flentke GR, et al. Alcohol Clin Exp Res, 2014 May. PMID 24512079, Free PMC Article
  2. Highly penetrant melanoma in a zebrafish model is independent of ErbB3b signaling. Santoriello C, et al. Pigment Cell Melanoma Res, 2012 Mar. PMID 22248380
  3. In situ hybridization assay-based small molecule screening in zebrafish. Jing L, et al. Curr Protoc Chem Biol, 2012 Jun 1. PMID 23001521, Free PMC Article
  4. Macondo crude oil from the Deepwater Horizon oil spill disrupts specific developmental processes during zebrafish embryogenesis. de Soysa TY, et al. BMC Biol, 2012 May 4. PMID 22559716, Free PMC Article
  5. A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates. Parker HJ, et al. Nat Commun, 2019 Mar 13. PMID 30867425, Free PMC Article

See all (184) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
crestin
Names
ctn

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_130993.2 → NP_571068.2  crestin

    Status: VALIDATED

    Source sequence(s)
    CR450840
    UniProtKB/TrEMBL
    A0A1D5NSV4, A0A8M1PAC0
    Related
    ENSDARP00000142925.1, ENSDART00000173868.2
    Conserved Domains (1) summary
    pfam08317
    Location:38 → 201
    Spc7; Spc7 kinetochore protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007115.7 Reference GRCz11 Primary Assembly

    Range
    47257854..47262290
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials