tapbp.1 TAP binding protein (tapasin), tandem duplicate 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tapbp.1provided by ZNC
Official Full Name: TAP binding protein (tapasin), tandem duplicate 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-010110-2
See related: Ensembl:ENSDARG00000079402 AllianceGenome:ZFIN:ZDB-GENE-010110-2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: tpsn; tapbp; mhc1uda; mhc1ufa; zgc:109814; SI:dZ179B20.1; SI:dZ179B20.3; SI:dZ179B20.7
Summary: Predicted to act upstream of or within antigen processing and presentation of endogenous peptide antigen via MHC class I. Predicted to be located in membrane. Is expressed in primordial germ cell. Human ortholog(s) of this gene implicated in severe combined immunodeficiency. Orthologous to human TAPBP (TAP binding protein). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 19

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (7038693..7043351, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (7119783..7124421, complement)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fi30c02.y1 (e-PCR)
- UniSTS:197231

Tjp1 (e-PCR), detects polymorphism
- UniSTS:144635

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within antigen processing and presentation of endogenous peptide antigen via MHC class I	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: TAP binding protein (tapasin), tandem duplicate 1

Names: TAP binding protein, tandem duplicate 1; tapasin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_130974.3 → NP_571049.2 TAP binding protein (tapasin), tandem duplicate 1 precursor

Status: VALIDATED

Source sequence(s)

FP085393

UniProtKB/TrEMBL

A0A8M2B6H1, Q1LUU3

Related

ENSDARP00000095615.4, ENSDART00000104845.6

Conserved Domains (1) summary

cl11960
Location:253 → 381

Ig; Immunoglobulin domain