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lft1 - lefty1

Predicted to enable cytokine activity. Acts upstream of or within determination of left/right symmetry; dorsal/ventral pattern formation; and embryonic heart tube development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including blastodisc; brain; germ ring; mesoderm; and tail bud. Human ortholog(s) of this gene implicated in congenital heart disease. Orthologous to several human genes including LEFTY2 (left-right determination factor 2). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to lft1

NCBI Orthologs

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Species Gene Architecture aa