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Asnsd1 asparagine synthetase domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 299507, updated on 27-Nov-2024

Summary

Official Symbol
Asnsd1provided by RGD
Official Full Name
asparagine synthetase domain containing 1provided by RGD
Primary source
RGD:1306332
See related
EnsemblRapid:ENSRNOG00000003942 AllianceGenome:RGD:1306332
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1306332
Summary
Predicted to enable asparagine synthase (glutamine-hydrolyzing) activity. Predicted to be involved in asparagine biosynthetic process and skeletal muscle tissue development. Predicted to act upstream of or within adipose tissue development; skeletal muscle organ development; and transdifferentiation. Orthologous to human ASNSD1 (asparagine synthetase domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 350.0), Muscle (RPKM 221.8) and 9 other tissues See more
Orthologs
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Genomic context

See Asnsd1 in Genome Data Viewer
Location:
9q22
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (55618799..55631064)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (48126808..48139073)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (52988042..53009054)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene glutamic-oxaloacetic transaminase 2, pseudogene 3 Neighboring gene solute carrier family 40 member 1 Neighboring gene proteolipid protein 2 like 1 Neighboring gene ASNSD1 upstream open reading frame Neighboring gene ankyrin and armadillo repeat containing Neighboring gene O-sialoglycoprotein endopeptidase-like 1 Neighboring gene PMS1 homolog 1, mismatch repair system component Neighboring gene ORMDL sphingolipid biosynthesis regulator 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
asparagine synthetase domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106763.1NP_001100233.1  asparagine synthetase domain-containing protein 1

    See identical proteins and their annotated locations for NP_001100233.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473965
    UniProtKB/TrEMBL
    A6INT9, D3ZWR3
    Related
    ENSRNOP00000056002.2, ENSRNOT00000059233.4
    Conserved Domains (2) summary
    cd01991
    Location:322603
    Asn_Synthase_B_C; The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the ...
    cd03766
    Location:1179
    Gn_AT_II_novel; This asparagine synthase-related domain is present in eukaryotes but its function has not yet been determined. The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    55618799..55631064
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)