GUCA2B - guanylate cyclase activator 2B
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and water homeostasis in the intestine and kidneys. [provided by RefSeq, Nov 2015]
NCBI Orthologs
How was this calculated?genes for:
Protein alignment
Download data
Species | Gene | Architecture | aa |
---|