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Snx30 sorting nexin family member 30 [ Rattus norvegicus (Norway rat) ]

Gene ID: 298033, updated on 4-Jan-2025

Summary

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Official Symbol
Snx30provided by RGD
Official Full Name
sorting nexin family member 30provided by RGD
Primary source
RGD:1311367
See related
EnsemblRapid:ENSRNOG00000017132 AllianceGenome:RGD:1311367
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1311367
Summary
Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in several processes, including endocytic recycling; macroautophagy; and positive regulation of autophagosome assembly. Predicted to be located in early endosome membrane. Predicted to be active in early endosome and phagophore assembly site. Orthologous to human SNX30 (sorting nexin family member 30). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Spleen (RPKM 132.8), Kidney (RPKM 121.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Snx30 in Genome Data Viewer
Location:
5q24
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (79478804..79608118)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (74683902..74813013)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (77052445..77161964)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene INTS3 and NABP interacting protein Neighboring gene transfer RNA serine (anticodon AGA) 22 Neighboring gene transfer RNA alanine (anticodon AGC) 81 Neighboring gene solute carrier family 46, member 2 Neighboring gene alpha-2u globulin PGCL4 Neighboring gene zinc finger protein 37, pseudogene 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in endocytic recycling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitophagy IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in piecemeal microautophagy of the nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of autophagosome assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein transport ISO
Inferred from Sequence Orthology
more info
  
involved_in reticulophagy IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in early endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in early endosome ISO
Inferred from Sequence Orthology
more info
  
located_in early endosome membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in phagophore assembly site IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
sorting nexin-30

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106651.1 → NP_001100121.1  sorting nexin-30

    See identical proteins and their annotated locations for NP_001100121.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474039
    UniProtKB/TrEMBL
    A6KDX6, D4A060
    Related
    ENSRNOP00000107590.1, ENSRNOT00000161925.1
    Conserved Domains (2) summary
    cd06860
    Location:91 → 206
    PX_SNX7_30_like; The phosphoinositide binding Phox Homology domain of Sorting Nexins 7 and 30
    cd07667
    Location:190 → 429
    BAR_SNX30; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 30

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    79478804..79608118
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063287322.1 → XP_063143392.1  sorting nexin-30 isoform X1

    UniProtKB/TrEMBL
    D4A060

  2. XM_063287324.1 → XP_063143394.1  sorting nexin-30 isoform X3

    UniProtKB/TrEMBL
    D4A060
    Related
    ENSRNOP00000056176.5, ENSRNOT00000059419.6

  3. XM_063287323.1 → XP_063143393.1  sorting nexin-30 isoform X2

    UniProtKB/TrEMBL
    D4A060
    Related
    ENSRNOP00000109497.1, ENSRNOT00000156988.1

  4. XM_039109447.2 → XP_038965375.1  sorting nexin-30 isoform X4

    UniProtKB/TrEMBL
    D4A060
    Related
    ENSRNOP00000102520.1, ENSRNOT00000157957.1
    Conserved Domains (2) summary
    cd06860
    Location:91 → 206
    PX_SNX7_30_like; The phosphoinositide binding Phox Homology domain of Sorting Nexins 7 and 30
    cl12013
    Location:190 → 422
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
Nucleotide Protein Strain
Heading Accession and Version

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