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Tmem245 transmembrane protein 245 [ Rattus norvegicus (Norway rat) ]

Gene ID: 298020, updated on 4-Jan-2025

Summary

Official Symbol
Tmem245provided by RGD
Official Full Name
transmembrane protein 245provided by RGD
Primary source
RGD:1308958
See related
EnsemblRapid:ENSRNOG00000026271 AllianceGenome:RGD:1308958
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308958
Summary
Predicted to be located in membrane. Orthologous to human TMEM245 (transmembrane protein 245). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Heart (RPKM 219.3), Adrenal (RPKM 168.4) and 9 other tissues See more
Orthologs
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Genomic context

See Tmem245 in Genome Data Viewer
Location:
5q24
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (76366157..76443108, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (71570952..71647915, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (73909032..73986602, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene elongator acetyltransferase complex subunit 1 Neighboring gene actin binding transcription modulator Neighboring gene catenin alpha-like 1 Neighboring gene microRNA 32 Neighboring gene ferric-chelate reductase 1-like Neighboring gene erythrocyte membrane protein band 4.1 like 4B

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001419571.2NP_001406500.1  transmembrane protein 245

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/Swiss-Prot
    D3ZXD8
    UniProtKB/TrEMBL
    D3ZR79
    Related
    ENSRNOP00000035996.4, ENSRNOT00000032299.7

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    76366157..76443108 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008763737.3XP_008761959.1  transmembrane protein 245 isoform X4

    See identical proteins and their annotated locations for XP_008761959.1

    UniProtKB/TrEMBL
    D3ZR79
    Related
    ENSRNOP00000079058.2, ENSRNOT00000103281.2
    Conserved Domains (1) summary
    cl00465
    Location:616806
    UPF0118; Domain of unknown function DUF20
  2. XM_039111408.2XP_038967336.1  transmembrane protein 245 isoform X3

    UniProtKB/TrEMBL
    A0A8I5ZM20, D3ZR79
    Related
    ENSRNOP00000103723.1, ENSRNOT00000151825.1
    Conserved Domains (1) summary
    cl00465
    Location:583829
    AI-2E_transport; AI-2E family transporter
  3. XM_216388.10XP_216388.4  transmembrane protein 245 isoform X2

    See identical proteins and their annotated locations for XP_216388.4

    UniProtKB/TrEMBL
    A0A8I6AGG4, D3ZR79
    Related
    ENSRNOP00000093041.1, ENSRNOT00000116562.2
    Conserved Domains (1) summary
    cl00465
    Location:651841
    UPF0118; Domain of unknown function DUF20
  4. XM_006238188.4XP_006238250.1  transmembrane protein 245 isoform X1

    See identical proteins and their annotated locations for XP_006238250.1

    UniProtKB/TrEMBL
    D3ZR79
    Related
    ENSRNOP00000063739.3, ENSRNOT00000064043.6
    Conserved Domains (1) summary
    cl00465
    Location:659849
    UPF0118; Domain of unknown function DUF20
  5. XM_039111410.2XP_038967338.1  transmembrane protein 245 isoform X6

    Conserved Domains (1) summary
    cl00465
    Location:214404
    AI-2E_transport; AI-2E family transporter
  6. XM_063287307.1XP_063143377.1  transmembrane protein 245 isoform X5