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Zc3hc1 zinc finger, C3HC-type containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 296957, updated on 27-Nov-2024

Summary

Official Symbol
Zc3hc1provided by RGD
Official Full Name
zinc finger, C3HC-type containing 1provided by RGD
Primary source
RGD:1561099
See related
EnsemblRapid:ENSRNOG00000010154 AllianceGenome:RGD:1561099
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1561099
Summary
Predicted to enable protein kinase binding activity. Predicted to be located in nuclear membrane and nucleoplasm. Predicted to be part of nuclear pore nuclear basket. Predicted to be active in nucleus. Orthologous to human ZC3HC1 (zinc finger C3HC-type containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 123.1), Spleen (RPKM 82.7) and 9 other tissues See more
Orthologs
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Genomic context

See Zc3hc1 in Genome Data Viewer
Location:
4q22
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (59957402..59979336, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (58989989..59011925, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (57684678..57706613, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2H Neighboring gene small nucleolar RNA SNORA32 Neighboring gene kelch domain containing 10 Neighboring gene uncharacterized LOC134486570 Neighboring gene uncharacterized LOC108350685

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nuclear membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
 
part_of nuclear pore nuclear basket ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
zinc finger C3HC-type protein 1
Names
nuclear-interacting partner of ALK
zinc finger, C3HC-type 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127293.1NP_001120765.1  zinc finger C3HC-type protein 1

    See identical proteins and their annotated locations for NP_001120765.1

    Status: PROVISIONAL

    Source sequence(s)
    BC166834
    UniProtKB/TrEMBL
    A0A140UHX2, A0A8I6AJ97, B2RYM6, F1MAI0
    Related
    ENSRNOP00000013606.8, ENSRNOT00000013604.9
    Conserved Domains (2) summary
    pfam07967
    Location:73201
    zf-C3HC; C3HC zinc finger-like
    pfam08600
    Location:248337
    Rsm1; Rsm1-like

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    59957402..59979336 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)