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Zfp341 zinc finger protein 341 [ Rattus norvegicus (Norway rat) ]

Gene ID: 296300, updated on 4-Jan-2025

Summary

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Symbol
Zfp341provided by RGD
Full Name
zinc finger protein 341provided by RGD
Primary source
RGD:1564726
See related
EnsemblRapid:ENSRNOG00000017086 AllianceGenome:RGD:1564726
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Zfp966; Znf341; LRRGT00145; AABR07054367.1
Summary
Predicted to enable DNA-binding transcription activator activity and chromatin insulator sequence binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in chromosome. Human ortholog(s) of this gene implicated in hyper IgE recurrent infection syndrome 3. Orthologous to human ZNF341 (zinc finger protein 341). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Brain (RPKM 25.2), Lung (RPKM 22.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfp341 in Genome Data Viewer
Location:
3q41
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (163582937..163616448)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (143122699..143156250)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (150114853..150172425)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene peroxisomal membrane protein 4 Neighboring gene small nuclear ribonucleoprotein polypeptide E like 3 Neighboring gene transfer RNA alanine (anticodon AGC) 3 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 like 2 Neighboring gene charged multivesicular body protein 4B Neighboring gene uncharacterized LOC134486467

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. ZNF341 controls STAT3 expression and thereby immunocompetence. Frey-Jakobs S, et al. Sci Immunol, 2018 Jun 15. PMID 29907690, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables DNA-binding transcription activator activity ISO
Inferred from Sequence Orthology
more info
  
enables chromatin insulator sequence binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in chromosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
zinc finger protein 341
Names
zinc finger protein 966

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001430392.1 → NP_001417321.1  zinc finger protein 341 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A6KI01, F7ETL6

  2. NM_001430393.1 → NP_001417322.1  zinc finger protein 341 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A6KI01

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    163582937..163616448
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008762405.4 → XP_008760627.2  zinc finger protein 341 isoform X1

    Related
    ENSRNOP00000043308.4, ENSRNOT00000047286.5
    Conserved Domains (3) summary
    COG5048
    Location:321 → 726
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:565 → 585
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:539 → 561
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_039106691.2 → XP_038962619.1  zinc finger protein 341 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:314 → 719
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:558 → 578
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:532 → 554
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_039106692.2 → XP_038962620.1  zinc finger protein 341 isoform X3

    UniProtKB/TrEMBL
    A6KI01
    Conserved Domains (2) summary
    COG5048
    Location:254 → 659
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:498 → 518
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. XM_063285100.1 → XP_063141170.1  zinc finger protein 341 isoform X4

    UniProtKB/TrEMBL
    A6KI01

  5. XM_039106694.1 → XP_038962622.1  zinc finger protein 341 isoform X5

    Conserved Domains (2) summary
    COG5048
    Location:42 → 447
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:286 → 306
    ZF_C2H2; C2H2 Zn finger [structural motif]

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001047859.1: Suppressed sequence

    Description
    NM_001047859.1: This RefSeq was removed because the CDS was partial.
Nucleotide Protein Strain
Heading Accession and Version

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