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St7l suppression of tumorigenicity 7-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 295344, updated on 27-Nov-2024

Summary

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Official Symbol
St7lprovided by RGD
Official Full Name
suppression of tumorigenicity 7-likeprovided by RGD
Primary source
RGD:1359336
See related
EnsemblRapid:ENSRNOG00000014002 AllianceGenome:RGD:1359336
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in negative regulation of cell growth. Predicted to be located in membrane and ribosome. Predicted to be part of ribonucleoprotein complex. Orthologous to human ST7L (suppression of tumorigenicity 7 like). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 71.7), Heart (RPKM 67.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See St7l in Genome Data Viewer
Location:
2q34
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (195052939..195122755)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (192364594..192434414)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (207350651..207421082)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene ras homolog family member C Neighboring gene Mov10 RNA helicase Neighboring gene capping actin protein of muscle Z-line subunit alpha 1 Neighboring gene Wnt family member 2B Neighboring gene small ribosomal subunit protein eS6-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. ST7-mediated suppression of tumorigenicity of prostate cancer cells is characterized by remodeling of the extracellular matrix. Hooi CF, et al. Oncogene, 2006 Jun 29. PMID 16474848
  2. Molecular cloning and characterization of mouse St7r (St7-like, St7l). Saitoh T, et al. Int J Mol Med, 2002 Jul. PMID 12060862
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC94245

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of cell growth IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of cell growth ISO
Inferred from Sequence Orthology
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
suppressor of tumorigenicity 7 protein-like
Names
suppressor of tumorigenicity protein 7-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007639.1 → NP_001007640.1  suppressor of tumorigenicity 7 protein-like

    See identical proteins and their annotated locations for NP_001007640.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079194
    UniProtKB/Swiss-Prot
    Q68FW3
    UniProtKB/TrEMBL
    A0A0G2K7G8, A6K3Q1
    Related
    ENSRNOP00000109875.1, ENSRNOT00000158468.1
    Conserved Domains (1) summary
    cd11557
    Location:75 → 542
    ST7; Suppression of tumorigenicity 7

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    195052939..195122755
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063281643.1 → XP_063137713.1  suppressor of tumorigenicity 7 protein-like isoform X1

  2. XM_063281644.1 → XP_063137714.1  suppressor of tumorigenicity 7 protein-like isoform X2

  3. XM_063281647.1 → XP_063137717.1  suppressor of tumorigenicity 7 protein-like isoform X4

  4. XM_063281646.1 → XP_063137716.1  suppressor of tumorigenicity 7 protein-like isoform X3

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q68FW3.1 GenPept UniProtKB/Swiss-Prot:Q68FW3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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