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Slc7a12 solute carrier family 7 (cationic amino acid transporter, y+ system), member 12 [ Rattus norvegicus (Norway rat) ]

Gene ID: 294881, updated on 4-Jan-2025

Summary

Official Symbol
Slc7a12provided by RGD
Official Full Name
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12provided by RGD
Primary source
RGD:1309208
See related
EnsemblRapid:ENSRNOG00000033830 AllianceGenome:RGD:1309208
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to act upstream of or within amino acid transport. Predicted to be located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Jan 2025]
Expression
Restricted expression toward (RPKM 843.1) See more
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Genomic context

See Slc7a12 in Genome Data Viewer
Location:
2q23
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (88800954..88868117, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (87079724..87146875, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (88559677..88660449, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene transfer RNA proline (anticodon AGG) Neighboring gene E2F transcription factor 5 Neighboring gene leucine rich repeat and coiled-coil centrosomal protein 1 Neighboring gene solute carrier family 7 member 13, pseudogene 1 Neighboring gene leucine-rich repeat and coiled-coil domain-containing protein 1-like Neighboring gene uncharacterized LOC134485875

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Clone Names

  • MGC94806

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables amino acid transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in L-alpha-amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within amino acid transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011948.1NP_001011948.1  solute carrier family 7 (cationic amino acid transporter, y+ system), member 12

    See identical proteins and their annotated locations for NP_001011948.1

    Status: PROVISIONAL

    Source sequence(s)
    BC078940
    UniProtKB/TrEMBL
    Q6AYR7
    Related
    ENSRNOP00000050128.2, ENSRNOT00000051741.6
    Conserved Domains (1) summary
    TIGR00911
    Location:21423
    2A0308; L-type amino acid transporter

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    88800954..88868117 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063281531.1XP_063137601.1  solute carrier family 7 (cationic amino acid transporter, y+ system), member 12 isoform X1