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Calhm6 calcium homeostasis modulator family member 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 294430, updated on 27-Nov-2024

Summary

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Official Symbol
Calhm6provided by RGD
Official Full Name
calcium homeostasis modulator family member 6provided by RGD
Primary source
RGD:1304835
See related
EnsemblRapid:ENSRNOG00000037757 AllianceGenome:RGD:1304835
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fam26f; RGD1304835
Summary
Predicted to enable monoatomic cation channel activity. Predicted to be involved in ATP export; monoatomic cation transmembrane transport; and regulation of natural killer cell cytokine production. Predicted to be located in immunological synapse. Predicted to be active in plasma membrane. Orthologous to human CALHM6 (calcium homeostasis modulator family member 6). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 86.5), Thymus (RPKM 32.2) and 6 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Calhm6 in Genome Data Viewer
Location:
20q11
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (26638721..26640466, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (26095591..26097336, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (27681138..27683580, complement)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex subunit 3L Neighboring gene calcium homeostasis modulator family member 4 Neighboring gene calcium homeostasis modulator family member 5 Neighboring gene dermatan sulfate epimerase Neighboring gene eukaryotic translation elongation factor 1 alpha 1, pseudogene 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables monoatomic cation channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables voltage-gated channel activity IEA
Inferred from Electronic Annotation
more info
  
enables voltage-gated channel activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in ATP export IEA
Inferred from Electronic Annotation
more info
  
involved_in ATP export ISO
Inferred from Sequence Orthology
more info
  
involved_in monoatomic cation transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of natural killer cell cytokine production IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of natural killer cell cytokine production ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in immunological synapse IEA
Inferred from Electronic Annotation
more info
  
located_in immunological synapse ISO
Inferred from Sequence Orthology
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
calcium homeostasis modulator protein 6
Names
family with sequence similarity 26, member F
protein FAM26F

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024976.1 → NP_001020147.1  calcium homeostasis modulator protein 6

    See identical proteins and their annotated locations for NP_001020147.1

    Status: PROVISIONAL

    Source sequence(s)
    BC093379
    UniProtKB/Swiss-Prot
    Q561R8
    UniProtKB/TrEMBL
    A6K3S8
    Related
    ENSRNOP00000054134.2, ENSRNOT00000057317.6
    Conserved Domains (1) summary
    pfam14798
    Location:2 → 246
    Ca_hom_mod; Calcium homeostasis modulator

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    26638721..26640466 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008772880.3 → XP_008771102.1  calcium homeostasis modulator protein 6 isoform X1

    Conserved Domains (1) summary
    pfam14798
    Location:4 → 173
    Ca_hom_mod; Calcium homeostasis modulator
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q561R8.1 GenPept UniProtKB/Swiss-Prot:Q561R8

Gene LinkOut

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