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Zfp275 zinc finger protein 275 [ Rattus norvegicus (Norway rat) ]

Gene ID: 293849, updated on 9-Dec-2024

Summary

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Official Symbol
Zfp275provided by RGD
Official Full Name
zinc finger protein 275provided by RGD
Primary source
RGD:1564630
See related
EnsemblRapid:ENSRNOG00000061073 AllianceGenome:RGD:1564630
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1564630
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF275 (zinc finger protein 275). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Spleen (RPKM 66.6), Adrenal (RPKM 59.5) and 9 other tissues See more
Orthologs
human all
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Genomic context

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See Zfp275 in Genome Data Viewer
Location:
Xq37
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (156208873..156225732)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (151057530..151074392)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (157457399..157474263, complement)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene dnaJ homolog subfamily C member 8-like Neighboring gene PWWP domain containing 4 Neighboring gene U2 spliceosomal RNA Neighboring gene PNMA family member 6E Neighboring gene ZFP92 zinc finger protein Neighboring gene potassium two pore domain channel subfamily K member 6, pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 275

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106343.1 → NP_001099813.1  zinc finger protein 275

    See identical proteins and their annotated locations for NP_001099813.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474099
    UniProtKB/TrEMBL
    A6KRY9, D3ZRH5
    Related
    ENSRNOP00000075303.1, ENSRNOT00000079860.3
    Conserved Domains (4) summary
    COG5048
    Location:252 → 493
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:202 → 274
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:365 → 385
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:171 → 191
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    156208873..156225732
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039099527.2 → XP_038955455.1  zinc finger protein 275 isoform X4

    Conserved Domains (2) summary
    COG5048
    Location:82 → 341
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:213 → 233
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_063279835.1 → XP_063135905.1  zinc finger protein 275 isoform X3

  3. XM_039099524.2 → XP_038955452.1  zinc finger protein 275 isoform X1

    UniProtKB/TrEMBL
    A6KRY9, D3ZRH5
    Conserved Domains (4) summary
    COG5048
    Location:252 → 493
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:202 → 274
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:365 → 385
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:171 → 191
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. XM_039099526.2 → XP_038955454.1  zinc finger protein 275 isoform X3

    Conserved Domains (4) summary
    COG5048
    Location:130 → 371
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:80 → 152
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:243 → 263
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:49 → 69
    ZF_C2H2; C2H2 Zn finger [structural motif]

  5. XM_039099528.2 → XP_038955456.1  zinc finger protein 275 isoform X3

    Conserved Domains (4) summary
    COG5048
    Location:130 → 371
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:80 → 152
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:243 → 263
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:49 → 69
    ZF_C2H2; C2H2 Zn finger [structural motif]

  6. XM_039099525.2 → XP_038955453.1  zinc finger protein 275 isoform X2

    Conserved Domains (4) summary
    COG5048
    Location:217 → 458
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:167 → 239
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:330 → 350
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:136 → 156
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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