U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tbc1d17 TBC1 domain family, member 17 [ Rattus norvegicus (Norway rat) ]

Gene ID: 292886, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
Tbc1d17provided by RGD
Official Full Name
TBC1 domain family, member 17provided by RGD
Primary source
RGD:1309686
See related
EnsemblRapid:ENSRNOG00000020191 AllianceGenome:RGD:1309686
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in retrograde transport, endosome to Golgi. Predicted to be located in cytosol. Orthologous to human TBC1D17 (TBC1 domain family member 17). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Adrenal (RPKM 126.6), Kidney (RPKM 115.4) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Tbc1d17 in Genome Data Viewer
Location:
1q22
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (104461266..104469615, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (95324770..95333156, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (100836993..100845216, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene VRK serine/threonine kinase 3 Neighboring gene activating transcription factor 5 Neighboring gene nucleoporin 62 Neighboring gene interleukin 4 induced 1 Neighboring gene AKT1 substrate 1 Neighboring gene polynucleotide kinase 3'-phosphatase

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways. Fuchs E, et al. J Cell Biol, 2007 Jun 18. PMID 17562788, Free PMC Article
  2. Functional dissection of Rab GTPases involved in primary cilium formation. Yoshimura S, et al. J Cell Biol, 2007 Jul 30. PMID 17646400, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
NOT involved_in regulation of cilium assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in retrograde transport, endosome to Golgi ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
TBC1 domain family member 17

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106258.2 → NP_001099728.1  TBC1 domain family member 17

    See identical proteins and their annotated locations for NP_001099728.1

    Status: PROVISIONAL

    Source sequence(s)
    BC160880
    UniProtKB/TrEMBL
    A0A8I6ARY2, A6JAS9, B1H264, F7F3L4
    Related
    ENSRNOP00000027436.7, ENSRNOT00000027436.8
    Conserved Domains (2) summary
    pfam12068
    Location:3 → 218
    DUF3548; Domain of unknown function (DUF3548)
    smart00164
    Location:308 → 543
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    104461266..104469615 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039104825.2 → XP_038960753.1  TBC1 domain family member 17 isoform X1

    UniProtKB/TrEMBL
    F7F3L4
    Related
    ENSRNOP00000106881.1, ENSRNOT00000126829.1
    Conserved Domains (2) summary
    smart00164
    Location:308 → 517
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    pfam12068
    Location:7 → 205
    DUF3548; Domain of unknown function (DUF3548)

  2. XM_063283976.1 → XP_063140046.1  TBC1 domain family member 17 isoform X2

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous