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Fam98c family with sequence similarity 98, member C [ Rattus norvegicus (Norway rat) ]

Gene ID: 292764, updated on 27-Nov-2024

Summary

Official Symbol
Fam98cprovided by RGD
Official Full Name
family with sequence similarity 98, member Cprovided by RGD
Primary source
RGD:1303117
See related
EnsemblRapid:ENSRNOG00000024036 AllianceGenome:RGD:1303117
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1303117
Summary
Predicted to be part of tRNA-splicing ligase complex. Orthologous to human FAM98C (family with sequence similarity 98 member C). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 74.2), Spleen (RPKM 63.3) and 9 other tissues See more
Orthologs
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Genomic context

See Fam98c in Genome Data Viewer
Location:
1q21
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (93580286..93583894, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (84452806..84456414, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (88095240..88098828, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene MARCKS-related protein-like Neighboring gene mitogen activated protein kinase kinase kinase kinase 1 Neighboring gene ryanodine receptor 1 Neighboring gene RAS guanyl releasing protein 4 Neighboring gene sprouty-related, EVH1 domain containing 3 Neighboring gene gametogenetin

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001198584.1NP_001185513.1  protein FAM98C

    See identical proteins and their annotated locations for NP_001185513.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes a 344aa protein.
    Source sequence(s)
    BC079080, CO564588, CO570848
    UniProtKB/TrEMBL
    F1LQ27
    Related
    ENSRNOP00000053799.4, ENSRNOT00000056964.5
    Conserved Domains (1) summary
    pfam10239
    Location:10325
    DUF2465; Protein of unknown function (DUF2465)

RNA

  1. NR_037147.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an additional segment in the 5' region, as compared to variant 1. The transcript is a nonsense-mediated mRNA decay candidate and probably does not make a protein.
    Source sequence(s)
    BC079080, CO570848

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    93580286..93583894 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006228717.4XP_006228779.1  protein FAM98C isoform X1

    See identical proteins and their annotated locations for XP_006228779.1

    UniProtKB/TrEMBL
    F1LQ27
    Conserved Domains (1) summary
    pfam10239
    Location:10325
    DUF2465; Protein of unknown function (DUF2465)
  2. XM_063283452.1XP_063139522.1  protein FAM98C isoform X3

  3. XM_063283450.1XP_063139520.1  protein FAM98C isoform X2

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001004219.1: Suppressed sequence

    Description
    NM_001004219.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.