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Etl4 enhancer trap locus 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 291356, updated on 27-Nov-2024

Summary

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Symbol
Etl4provided by RGD
Full Name
enhancer trap locus 4provided by RGD
Primary source
RGD:1563437
See related
EnsemblRapid:ENSRNOG00000008666 AllianceGenome:RGD:1563437
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563437
Summary
Predicted to be involved in embryonic skeletal system development. Predicted to be located in centrosome. Predicted to be active in cytoplasm. Orthologous to human KIAA1217 (KIAA1217). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 136.9), Heart (RPKM 84.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Etl4 in Genome Data Viewer
Location:
17q12.3
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (87749486..88213158)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (82841075..83304868)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (87173265..87681268)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L37-like Neighboring gene U6 spliceosomal RNA Neighboring gene NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3-like Neighboring gene uncharacterized LOC120097745 Neighboring gene Rho GTPase activating protein 21 Neighboring gene uncharacterized LOC102550154

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A novel murine gene, Sickle tail, linked to the Danforth's short tail locus, is required for normal development of the intervertebral disc. Semba K, et al. Genetics, 2006 Jan. PMID 16204209, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in embryonic skeletal system development ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
sickle tail protein homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427790.1 → NP_001414719.1  sickle tail protein homolog

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000017
    UniProtKB/TrEMBL
    A0A8I5YBN1
    Related
    ENSRNOP00000077128.1, ENSRNOT00000116431.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    87749486..88213158
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063276268.1 → XP_063132338.1  sickle tail protein homolog isoform X1

  2. XM_008771907.4 → XP_008770129.3  sickle tail protein homolog isoform X7

    UniProtKB/TrEMBL
    A0A8I6GEH8
    Conserved Domains (2) summary
    pfam03915
    Location:237 → 315
    AIP3; Actin interacting protein 3
    NF033930
    Location:693 → 952
    pneumo_PspA; pneumococcal surface protein A

  3. XM_039096217.2 → XP_038952145.1  sickle tail protein homolog isoform X2

    UniProtKB/TrEMBL
    A0A8I6GEH8
    Conserved Domains (2) summary
    pfam03915
    Location:237 → 315
    AIP3; Actin interacting protein 3
    NF033930
    Location:728 → 987
    pneumo_PspA; pneumococcal surface protein A

  4. XM_063276269.1 → XP_063132339.1  sickle tail protein homolog isoform X5

  5. XM_039096218.2 → XP_038952146.1  sickle tail protein homolog isoform X3

    UniProtKB/TrEMBL
    A0A8I6GEH8
    Related
    ENSRNOP00000086860.1, ENSRNOT00000114046.2
    Conserved Domains (2) summary
    pfam03915
    Location:237 → 315
    AIP3; Actin interacting protein 3
    NF033930
    Location:728 → 987
    pneumo_PspA; pneumococcal surface protein A

  6. XM_063276270.1 → XP_063132340.1  sickle tail protein homolog isoform X6

  7. XM_039096229.2 → XP_038952157.1  sickle tail protein homolog isoform X22

    UniProtKB/TrEMBL
    A0A8I6A455
    Conserved Domains (2) summary
    pfam03915
    Location:237 → 315
    AIP3; Actin interacting protein 3
    NF033930
    Location:728 → 987
    pneumo_PspA; pneumococcal surface protein A

  8. XM_039096227.2 → XP_038952155.1  sickle tail protein homolog isoform X21

    UniProtKB/TrEMBL
    A6JMB1
    Conserved Domains (2) summary
    pfam03915
    Location:237 → 315
    AIP3; Actin interacting protein 3
    NF033930
    Location:693 → 952
    pneumo_PspA; pneumococcal surface protein A

  9. XM_039096230.2 → XP_038952158.1  sickle tail protein homolog isoform X24

    UniProtKB/TrEMBL
    A0A8I6A4F8, A6JMB1
    Related
    ENSRNOP00000085969.1, ENSRNOT00000096341.2
    Conserved Domains (2) summary
    pfam03915
    Location:188 → 266
    AIP3; Actin interacting protein 3
    NF033930
    Location:644 → 903
    pneumo_PspA; pneumococcal surface protein A

  10. XM_039096219.2 → XP_038952147.1  sickle tail protein homolog isoform X4

    UniProtKB/TrEMBL
    M0R5H1
    Related
    ENSRNOP00000064638.3, ENSRNOT00000073718.5
    Conserved Domains (2) summary
    pfam03915
    Location:215 → 293
    AIP3; Actin interacting protein 3
    NF033930
    Location:706 → 965
    pneumo_PspA; pneumococcal surface protein A

  11. XM_063276271.1 → XP_063132341.1  sickle tail protein homolog isoform X8

  12. XM_039096221.2 → XP_038952149.1  sickle tail protein homolog isoform X9

    UniProtKB/TrEMBL
    M0R5H1
    Conserved Domains (2) summary
    pfam03915
    Location:188 → 266
    AIP3; Actin interacting protein 3
    NF033930
    Location:644 → 903
    pneumo_PspA; pneumococcal surface protein A

  13. XM_039096222.2 → XP_038952150.1  sickle tail protein homolog isoform X10

    UniProtKB/TrEMBL
    A0A8I6A6M2, M0R5H1
    Related
    ENSRNOP00000086839.1, ENSRNOT00000096762.2
    Conserved Domains (2) summary
    pfam03915
    Location:188 → 266
    AIP3; Actin interacting protein 3
    NF033930
    Location:644 → 903
    pneumo_PspA; pneumococcal surface protein A

  14. XM_063276281.1 → XP_063132351.1  sickle tail protein homolog isoform X23

  15. XM_039096231.2 → XP_038952159.1  sickle tail protein homolog isoform X25

    UniProtKB/TrEMBL
    A0A8I6A455
    Related
    ENSRNOP00000087978.2, ENSRNOT00000107420.2
    Conserved Domains (2) summary
    pfam03915
    Location:188 → 266
    AIP3; Actin interacting protein 3
    NF033930
    Location:679 → 938
    pneumo_PspA; pneumococcal surface protein A

  16. XM_039096223.2 → XP_038952151.1  sickle tail protein homolog isoform X11

    UniProtKB/TrEMBL
    M0R5H1
    Conserved Domains (2) summary
    pfam03915
    Location:104 → 182
    AIP3; Actin interacting protein 3
    NF033930
    Location:595 → 854
    pneumo_PspA; pneumococcal surface protein A

  17. XM_063276272.1 → XP_063132342.1  sickle tail protein homolog isoform X12

  18. XM_039096224.2 → XP_038952152.1  sickle tail protein homolog isoform X13

    UniProtKB/TrEMBL
    M0R5H1
    Conserved Domains (2) summary
    pfam03915
    Location:38 → 116
    AIP3; Actin interacting protein 3
    NF033930
    Location:529 → 788
    pneumo_PspA; pneumococcal surface protein A

  19. XM_063276280.1 → XP_063132350.1  sickle tail protein homolog isoform X20

  20. XM_063276275.1 → XP_063132345.1  sickle tail protein homolog isoform X16

  21. XM_039096225.2 → XP_038952153.1  sickle tail protein homolog isoform X14

    UniProtKB/TrEMBL
    M0R5H1
    Conserved Domains (1) summary
    NF033930
    Location:397 → 656
    pneumo_PspA; pneumococcal surface protein A

  22. XM_063276273.1 → XP_063132343.1  sickle tail protein homolog isoform X15

  23. XM_063276276.1 → XP_063132346.1  sickle tail protein homolog isoform X17

  24. XM_063276279.1 → XP_063132349.1  sickle tail protein homolog isoform X19

  25. XM_063276284.1 → XP_063132354.1  sickle tail protein homolog isoform X28

    Related
    ENSRNOP00000092656.1, ENSRNOT00000102713.2

  26. XM_063276282.1 → XP_063132352.1  sickle tail protein homolog isoform X26

  27. XM_063276278.1 → XP_063132348.1  sickle tail protein homolog isoform X18

  28. XM_039096226.2 → XP_038952154.1  sickle tail protein homolog isoform X14

    UniProtKB/TrEMBL
    M0R5H1
    Conserved Domains (1) summary
    NF033930
    Location:397 → 656
    pneumo_PspA; pneumococcal surface protein A

  29. XM_063276274.1 → XP_063132344.1  sickle tail protein homolog isoform X15

  30. XM_063276277.1 → XP_063132347.1  sickle tail protein homolog isoform X17

  31. XM_063276283.1 → XP_063132353.1  sickle tail protein homolog isoform X27

Nucleotide Protein Strain
Heading Accession and Version

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