U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tma16 translation machinery associated 16 homolog [ Rattus norvegicus (Norway rat) ]

Gene ID: 290686, updated on 27-Nov-2024

Summary

Official Symbol
Tma16provided by RGD
Official Full Name
translation machinery associated 16 homologprovided by RGD
Primary source
RGD:1305222
See related
EnsemblRapid:ENSRNOG00000089425 AllianceGenome:RGD:1305222
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305222
Summary
Predicted to enable preribosome binding activity. Predicted to be involved in ribosomal large subunit biogenesis. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in nucleus. Orthologous to human TMA16 (translation machinery associated 16 homolog). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 32.7), Brain (RPKM 30.6) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Tma16 in Genome Data Viewer
Location:
16p14
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (28003002..28021875)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (23236686..23252706)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (24978429..24997286)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene arginine/serine-rich protein PNISR-like Neighboring gene transketolase-like 2 Neighboring gene membrane associated ring-CH-type finger 1 Neighboring gene 60S ribosomal protein L22-like 1 pseudogene Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables preribosome binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in ribosomal large subunit biogenesis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
translation machinery-associated protein 16

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001169102.1NP_001162573.1  translation machinery-associated protein 16

    See identical proteins and their annotated locations for NP_001162573.1

    Status: VALIDATED

    Source sequence(s)
    BI294760, CF109688, JAXUCZ010000016
    UniProtKB/TrEMBL
    A0A8I6AC99, D4AAG0
    Conserved Domains (1) summary
    pfam11176
    Location:13161
    DUF2962; Protein of unknown function (DUF2962)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    28003002..28021875
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017600038.3XP_017455527.1  translation machinery-associated protein 16 isoform X1

    UniProtKB/TrEMBL
    A0A8I6AC99
    Related
    ENSRNOP00000101321.1, ENSRNOT00000142434.1