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Ocel1 occludin/ELL domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 290628, updated on 2-Nov-2024

Summary

Official Symbol
Ocel1provided by RGD
Official Full Name
occludin/ELL domain containing 1provided by RGD
Primary source
RGD:1565407
See related
EnsemblRapid:ENSRNOG00000032575 AllianceGenome:RGD:1565407
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563236; RGD1565407
Summary
Predicted to be involved in bicellular tight junction assembly. Predicted to be active in apical plasma membrane; bicellular tight junction; and cytoplasmic vesicle. Orthologous to human OCEL1 (occludin/ELL domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 54.2), Thymus (RPKM 53.8) and 9 other tissues See more
Orthologs
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Genomic context

See Ocel1 in Genome Data Viewer
Location:
16p14
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (18076428..18079068)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (18042037..18045080)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (19766728..19769034)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene myosin IXb Neighboring gene unconventional SNARE in the ER 1 Neighboring gene nuclear receptor subfamily 2, group F, member 6 Neighboring gene USH1 protein network component harmonin binding protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Clone Names

  • MGC189548

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in bicellular tight junction assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in bicellular tight junction IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytoplasmic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
occludin/ELL domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106065.1NP_001099535.1  occludin/ELL domain-containing protein 1

    See identical proteins and their annotated locations for NP_001099535.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474031
    UniProtKB/TrEMBL
    A6K9S4, D3ZE98
    Related
    ENSRNOP00000048493.4, ENSRNOT00000051802.5
    Conserved Domains (1) summary
    pfam07303
    Location:113214
    Occludin_ELL; Occludin homology domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    18076428..18079068
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008771079.4XP_008769301.1  occludin/ELL domain-containing protein 1 isoform X2

    Conserved Domains (1) summary
    pfam07303
    Location:116162
    Occludin_ELL; Occludin homology domain
  2. XM_006252856.5XP_006252918.1  occludin/ELL domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006252918.1

    UniProtKB/TrEMBL
    B5DFM2
    Conserved Domains (1) summary
    pfam07303
    Location:116252
    Occludin_ELL; Occludin homology domain
  3. XM_039094292.2XP_038950220.1  occludin/ELL domain-containing protein 1 isoform X3

    Conserved Domains (1) summary
    pfam07303
    Location:113183
    Occludin_ELL; Occludin homology domain
  4. XM_008771080.4XP_008769302.1  occludin/ELL domain-containing protein 1 isoform X4

    See identical proteins and their annotated locations for XP_008769302.1

    UniProtKB/TrEMBL
    A6K9S5, A6K9S6
    Related
    ENSRNOP00000106130.1, ENSRNOT00000151196.1