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Ccni cyclin I [ Rattus norvegicus (Norway rat) ]

Gene ID: 289500, updated on 2-Nov-2024

Summary

Official Symbol
Ccniprovided by RGD
Official Full Name
cyclin Iprovided by RGD
Primary source
RGD:1309209
See related
EnsemblRapid:ENSRNOG00000002125 AllianceGenome:RGD:1309209
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in G1/S transition of mitotic cell cycle. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human CCNI (cyclin I). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 661.1), Kidney (RPKM 601.9) and 9 other tissues See more
Orthologs
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Genomic context

See Ccni in Genome Data Viewer
Location:
14p22
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (15164047..15186885)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (14879698..14902510)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (16341510..16364326)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S3, pseudogene 2 Neighboring gene cyclin G2 Neighboring gene septin 11 Neighboring gene uncharacterized LOC134481828 Neighboring gene uncharacterized LOC134481721 Neighboring gene small nucleolar RNA SNORA70

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in G1/S transition of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of cyclin-dependent protein kinase holoenzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105998.1NP_001099468.1  cyclin-I

    See identical proteins and their annotated locations for NP_001099468.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474060
    UniProtKB/TrEMBL
    A6KK51, D4A5E4
    Related
    ENSRNOP00000002924.5, ENSRNOT00000002924.7
    Conserved Domains (1) summary
    cd20526
    Location:44142
    CYCLIN_CCNI-like; cyclin box found in cyclin-I (CCNI) and similar proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    15164047..15186885
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006250715.5XP_006250777.1  cyclin-I isoform X1

    See identical proteins and their annotated locations for XP_006250777.1

    UniProtKB/TrEMBL
    A6KK51, D4A5E4
    Conserved Domains (1) summary
    cd20526
    Location:44142
    CYCLIN_CCNI-like; cyclin box found in cyclin-I (CCNI) and similar proteins
  2. XM_063272900.1XP_063128970.1  cyclin-I isoform X2

    Related
    ENSRNOP00000105637.1, ENSRNOT00000137202.1