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Thsd7b thrombospondin type 1 domain containing 7B [ Rattus norvegicus (Norway rat) ]

Gene ID: 289007, updated on 9-Dec-2024

Summary

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Official Symbol
Thsd7bprovided by RGD
Official Full Name
thrombospondin type 1 domain containing 7Bprovided by RGD
Primary source
RGD:1306938
See related
EnsemblRapid:ENSRNOG00000003878 AllianceGenome:RGD:1306938
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1306938
Summary
Predicted to be involved in actin cytoskeleton organization. Predicted to be active in plasma membrane. Orthologous to human THSD7B (thrombospondin type 1 domain containing 7B). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Brain (RPKM 23.5), Adrenal (RPKM 11.6) and 3 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Thsd7b in Genome Data Viewer
Location:
13q13
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (43320895..44219546)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (40768567..41667262)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (46026943..46931619)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 26 Neighboring gene GABA type A receptor associated protein like 2, pseudogene 1 Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC120096244 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC134481489 Neighboring gene mitochondrial ribosomal protein L30, pseudogene 2 Neighboring gene CD55 molecule (Cromer blood group)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
thrombospondin type-1 domain-containing protein 7B
Names
thrombospondin, type I, domain containing 7B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191669.2 → NP_001178598.1  thrombospondin type-1 domain-containing protein 7B precursor

    See identical proteins and their annotated locations for NP_001178598.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000013
    UniProtKB/TrEMBL
    A0A8I5ZSV0, F1LPD7
    Related
    ENSRNOP00000081745.2, ENSRNOT00000115425.2
    Conserved Domains (2) summary
    pfam19028
    Location:337 → 398
    TSP1_spondin; Spondin-like TSP1 domain
    pfam19030
    Location:1063 → 1123
    TSP1_ADAMTS; Thrombospondin type 1 domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    43320895..44219546
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039090425.1 → XP_038946353.1  thrombospondin type-1 domain-containing protein 7B isoform X1

    Conserved Domains (2) summary
    pfam19028
    Location:337 → 398
    TSP1_spondin; Spondin-like TSP1 domain
    pfam19030
    Location:1063 → 1123
    TSP1_ADAMTS; Thrombospondin type 1 domain
Nucleotide Protein Strain
Heading Accession and Version

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