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Gadd45gip1 GADD45G interacting protein 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 288916, updated on 27-Nov-2024

Summary

Official Symbol
Gadd45gip1provided by RGD
Official Full Name
GADD45G interacting protein 1provided by RGD
Primary source
RGD:1309249
See related
EnsemblRapid:ENSRNOG00000003011 AllianceGenome:RGD:1309249
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
MRP-L59
Summary
Predicted to enable mitochondrial ribosome binding activity. Predicted to act upstream of or within positive regulation of cell population proliferation and positive regulation of oxidative phosphorylation. Predicted to be located in nucleoplasm. Predicted to be part of ribonucleoprotein complex. Predicted to be active in mitochondrion. Orthologous to human GADD45GIP1 (GADD45G interacting protein 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Muscle (RPKM 515.6), Adrenal (RPKM 376.1) and 9 other tissues See more
Orthologs
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Genomic context

See Gadd45gip1 in Genome Data Viewer
Location:
19q11
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (40225503..40228052, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (23320662..23323211, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (25946979..25949528)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene phenylalanyl-tRNA synthetase subunit alpha Neighboring gene calreticulin Neighboring gene RAD23 homolog A, nucleotide excision repair protein Neighboring gene uncharacterized LOC134483324 Neighboring gene DAN domain BMP antagonist family member 5 Neighboring gene uncharacterized LOC134483325 Neighboring gene nuclear factor I X

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RGD

Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
large ribosomal subunit protein mL64
Names
39S ribosomal protein L59, mitochondrial
growth arrest and DNA damage-inducible proteins-interacting protein 1
growth arrest and DNA-damage-inducible, gamma interacting protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100504.1NP_001093974.1  large ribosomal subunit protein mL64

    See identical proteins and their annotated locations for NP_001093974.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000019
    UniProtKB/Swiss-Prot
    Q5XJW2
    UniProtKB/TrEMBL
    A6IY72
    Related
    ENSRNOP00000004027.4, ENSRNOT00000004027.9
    Conserved Domains (1) summary
    pfam10147
    Location:1211
    CR6_interact; Growth arrest and DNA-damage-inducible proteins-interacting protein 1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    40225503..40228052 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)