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Cep95 centrosomal protein 95 [ Rattus norvegicus (Norway rat) ]

Gene ID: 287766, updated on 27-Nov-2024

Summary

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Official Symbol
Cep95provided by RGD
Official Full Name
centrosomal protein 95provided by RGD
Primary source
RGD:1309655
See related
EnsemblRapid:ENSRNOG00000014354 AllianceGenome:RGD:1309655
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ccdc45; RGD1309655
Summary
Predicted to be located in centrosome. Predicted to be active in spindle pole. Orthologous to human CEP95 (centrosomal protein 95). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 141.0), Adrenal (RPKM 104.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Cep95 in Genome Data Viewer
Location:
10q32.1
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (92231829..92259813)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (91732111..91760095)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (94988362..95017774)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene DNA polymerase gamma 2, accessory subunit Neighboring gene microRNA 3064 Neighboring gene DEAD-box helicase 5 Neighboring gene SMAD specific E3 ubiquitin protein ligase 2 Neighboring gene transfer RNA alanine (anticodon AGC) 91 Neighboring gene survival of motor neuron-related-splicing factor 30-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. Jakobsen L, et al. EMBO J, 2011 Apr 20. PMID 21399614, Free PMC Article
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in centrosome ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
  
located_in spindle pole ISO
Inferred from Sequence Orthology
more info
  
located_in spindle pole ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
centrosomal protein of 95 kDa
Names
centrosomal protein 95kDa
coiled-coil domain containing 45
coiled-coil domain-containing protein 45

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013862.1 → NP_001013884.1  centrosomal protein of 95 kDa

    See identical proteins and their annotated locations for NP_001013884.1

    Status: PROVISIONAL

    Source sequence(s)
    BC083896
    UniProtKB/Swiss-Prot
    Q5XI03
    UniProtKB/TrEMBL
    A0A8I6AJA7, A6HK61
    Related
    ENSRNOP00000101297.1, ENSRNOT00000168710.1
    Conserved Domains (1) summary
    TIGR02168
    Location:578 → 809
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    92231829..92259813
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017597144.3 → XP_017452633.1  centrosomal protein of 95 kDa isoform X1

    UniProtKB/TrEMBL
    A0A8I6AJA7, A0A8L2QW80
    Related
    ENSRNOP00000062563.3, ENSRNOT00000066525.4

  2. XM_063268755.1 → XP_063124825.1  centrosomal protein of 95 kDa isoform X2

  3. XM_039085634.2 → XP_038941562.1  centrosomal protein of 95 kDa isoform X4

    Conserved Domains (1) summary
    pfam19016
    Location:51 → 107
    DUF5745; Domain of unknown function (DUF5745)

  4. XM_039085633.2 → XP_038941561.1  centrosomal protein of 95 kDa isoform X3

    Conserved Domains (1) summary
    pfam19016
    Location:51 → 107
    DUF5745; Domain of unknown function (DUF5745)

  5. XM_063268756.1 → XP_063124826.1  centrosomal protein of 95 kDa isoform X5

  6. XM_039085635.2 → XP_038941563.1  centrosomal protein of 95 kDa isoform X6

    Conserved Domains (1) summary
    TIGR02168
    Location:198 → 433
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RNA

  1. XR_005489754.2 RNA Sequence

  2. XR_005489755.2 RNA Sequence

  3. XR_005489756.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XI03.1 GenPept UniProtKB/Swiss-Prot:Q5XI03

Gene LinkOut

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