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Zmynd15 zinc finger, MYND-type containing 15 [ Rattus norvegicus (Norway rat) ]

Gene ID: 287457, updated on 2-Nov-2024

Summary

Official Symbol
Zmynd15provided by RGD
Official Full Name
zinc finger, MYND-type containing 15provided by RGD
Primary source
RGD:1309845
See related
EnsemblRapid:ENSRNOG00000019477 AllianceGenome:RGD:1309845
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable histone deacetylase binding activity. Predicted to be involved in negative regulation of DNA-templated transcription and spermatid development. Predicted to be located in cytoplasm and male germ cell nucleus. Human ortholog(s) of this gene implicated in spermatogenic failure 14. Orthologous to human ZMYND15 (zinc finger MYND-type containing 15). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 81.5), Kidney (RPKM 34.8) and 6 other tissues See more
Orthologs
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Genomic context

See Zmynd15 in Genome Data Viewer
Location:
10q24
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (55669832..55676446)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (55171198..55177812)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (57064482..57071096)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene arrestin, beta 2 Neighboring gene mediator complex subunit 11 Neighboring gene C-X-C motif chemokine ligand 16 Neighboring gene transmembrane 4 L six family member 5 Neighboring gene vitelline membrane outer layer 1 homolog Neighboring gene glycolipid transfer protein domain containing 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables histone deacetylase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables histone deacetylase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within negative regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
 
involved_in spermatid development IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within spermatid development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in male germ cell nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
zinc finger MYND domain-containing protein 15
Names
zinc finger, MYND domain containing 15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105800.1NP_001099270.1  zinc finger MYND domain-containing protein 15

    See identical proteins and their annotated locations for NP_001099270.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473948
    UniProtKB/TrEMBL
    A0A8I5ZZM5, A6HG55, A6HG56, D4A1E1
    Related
    ENSRNOP00000084465.1, ENSRNOT00000113723.2
    Conserved Domains (1) summary
    pfam01753
    Location:309355
    zf-MYND; MYND finger

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    55669832..55676446
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006246662.5XP_006246724.1  zinc finger MYND domain-containing protein 15 isoform X1

    See identical proteins and their annotated locations for XP_006246724.1

    UniProtKB/TrEMBL
    A0A8I5ZZM5, A6HG55, A6HG56, D4A1E1
    Related
    ENSRNOP00000045805.4, ENSRNOT00000046807.6
    Conserved Domains (1) summary
    pfam01753
    Location:309355
    zf-MYND; MYND finger
  2. XM_006246661.4XP_006246723.1  zinc finger MYND domain-containing protein 15 isoform X1

    See identical proteins and their annotated locations for XP_006246723.1

    UniProtKB/TrEMBL
    A0A8I5ZZM5, A6HG55, A6HG56, D4A1E1
    Conserved Domains (1) summary
    pfam01753
    Location:309355
    zf-MYND; MYND finger