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Tmem256 transmembrane protein 256 [ Rattus norvegicus (Norway rat) ]

Gene ID: 287442, updated on 27-Nov-2024

Summary

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Official Symbol
Tmem256provided by RGD
Official Full Name
transmembrane protein 256provided by RGD
Primary source
RGD:1563438
See related
EnsemblRapid:ENSRNOG00000037540 AllianceGenome:RGD:1563438
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563438
Summary
Predicted to be located in mitochondrion. Predicted to be active in membrane. Orthologous to human TMEM256 (transmembrane protein 256). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 457.1), Heart (RPKM 456.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Tmem256 in Genome Data Viewer
Location:
10q24
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (55056959..55058869)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (54559030..54560146)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (56446022..56447138)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene spermatid maturation 1 Neighboring gene neuroligin 2 Neighboring gene phospholipid scramblase 3 Neighboring gene tyrosine kinase, non-receptor, 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Proteomic analysis of the mouse liver mitochondrial inner membrane. Da Cruz S, et al. J Biol Chem, 2003 Oct 17. PMID 12865426
  2. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
  3. Large-scale proteomics and phosphoproteomics of urinary exosomes. Gonzales PA, et al. J Am Soc Nephrol, 2009 Feb. PMID 19056867, Free PMC Article
  4. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
  5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 PubMed 

General protein information

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Preferred Names
transmembrane protein 256

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001170549.1 → NP_001164020.1  transmembrane protein 256

    See identical proteins and their annotated locations for NP_001164020.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A8I5YBI7, A6HFU3, F1LYI7
    Related
    ENSRNOP00000053711.2, ENSRNOT00000056870.6
    Conserved Domains (1) summary
    pfam04241
    Location:22 → 101
    DUF423; Protein of unknown function (DUF423)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    55056959..55058869
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063268641.1 → XP_063124711.1  transmembrane protein 256 isoform X1

    UniProtKB/TrEMBL
    A0A8I6AIZ6
    Related
    ENSRNOP00000111732.1, ENSRNOT00000163628.1

  2. XM_063268642.1 → XP_063124712.1  transmembrane protein 256 isoform X2

  3. XM_063268643.1 → XP_063124713.1  transmembrane protein 256 isoform X3

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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