Cfap144 cilia and flagella associated protein 144 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cfap144provided by RGD
Official Full Name: cilia and flagella associated protein 144provided by RGD
Primary source: RGD:1561932
See related: EnsemblRapid:ENSRNOG00000002873 AllianceGenome:RGD:1561932
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Fam183a; Fam183b; RGD1561932
Summary: Predicted to enable microtubule binding activity. Predicted to be located in axonemal microtubule; centrosome; and ciliary basal body. Predicted to be active in axonemal B tubule inner sheath and ciliary base. Orthologous to several human genes including CFAP144 (cilia and flagella associated protein 144). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 376.2) and Lung (RPKM 157.2) See more
Orthologs: human mouse all
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Genomic context

Location:: 10q22

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (44009412..44019281, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (43509823..43519693, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (44736547..44746907, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables microtubule binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in flagellated sperm motility	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in axonemal B tubule inner sheath	ISO Inferred from Sequence Orthology more info
located_in axonemal microtubule	ISO Inferred from Sequence Orthology more info
located_in centrosome	ISO Inferred from Sequence Orthology more info
located_in ciliary basal body	ISO Inferred from Sequence Orthology more info
is_active_in ciliary base	IBA Inferred from Biological aspect of Ancestor more info
is_active_in ciliary base	ISO Inferred from Sequence Orthology more info
is_active_in sperm flagellum	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: cilia- and flagella-associated protein 144

Names: family with sequence similarity 183 member A; family with sequence similarity 183, member B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001398580.1 → NP_001385509.1 cilia- and flagella-associated protein 144

Status: VALIDATED

Source sequence(s)

JAXUCZ010000010

UniProtKB/TrEMBL

A0A8I6AXW5, D3Z8P9

Related

ENSRNOP00000003841.4, ENSRNOT00000003841.9

Conserved Domains (1) summary

pfam14886
Location:21 → 123

FAM183; FAM183A and FAM183B related