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GDF7 growth differentiation factor 7 [ Bos taurus (domestic cattle) ]

Gene ID: 286859, updated on 1-Jan-2025

Summary

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Official Symbol
GDF7provided by VGNC
Official Full Name
growth differentiation factor 7provided by VGNC
Primary source
VGNC:VGNC:29305
See related
Ensembl:ENSBTAG00000038224
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See GDF7 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (78204301..78208326, complement)

Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene lactate dehydrogenase B pseudogene Neighboring gene lipid droplet associated hydrolase Neighboring gene uncharacterized LOC132346612 Neighboring gene uncharacterized LOC112448819 Neighboring gene HCLS1 binding protein 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. Gene expression of growth and differentiation factors-5, -6, and -7 in developing bovine tooth at the root forming stage. Morotome Y, et al. Biochem Biophys Res Commun, 1998 Mar 6. PMID 9514880
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
growth/differentiation factor 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001206101.1 → NP_001193030.1  growth/differentiation factor 7 precursor

    See identical proteins and their annotated locations for NP_001193030.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000011
    UniProtKB/TrEMBL
    F6QT88
    Related
    ENSBTAP00000052102.2, ENSBTAT00000056229.3
    Conserved Domains (2) summary
    smart00204
    Location:352 → 450
    TGFB; Transforming growth factor-beta (TGF-beta) family
    pfam00688
    Location:82 → 234
    TGFb_propeptide; TGF-beta propeptide

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    78204301..78208326 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials