U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PRDX2 peroxiredoxin 2 [ Bos taurus (domestic cattle) ]

Gene ID: 286793, updated on 27-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
PRDX2provided by VGNC
Official Full Name
peroxiredoxin 2provided by VGNC
Primary source
VGNC:VGNC:33300
See related
BGD:BT10759; Ensembl:ENSBTAG00000012062
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See PRDX2 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (12730404..12733442)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene retbindin Neighboring gene ribonuclease H2 subunit A Neighboring gene JunB proto-oncogene, AP-1 transcription factor subunit Neighboring gene hook microtubule tethering protein 2

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Cloning of bovine peroxiredoxins-gene expression in bovine tissues and amino acid sequence comparison with rat, mouse and primate peroxiredoxins. Leyens G, et al. Comp Biochem Physiol B Biochem Mol Biol, 2003 Dec. PMID 14662316
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables thioredoxin peroxidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell redox homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hydrogen peroxide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in leukocyte activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in removal of superoxide radicals IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to oxidative stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
peroxiredoxin-2
Names
thioredoxin-dependent peroxiredoxin 2
NP_777188.1
XP_005208710.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174763.2 → NP_777188.1  peroxiredoxin-2

    See identical proteins and their annotated locations for NP_777188.1

    Status: PROVISIONAL

    Source sequence(s)
    AF305562
    UniProtKB/Swiss-Prot
    Q3T0L0, Q9BGI3
    UniProtKB/TrEMBL
    A0AAA9RUA3
    Conserved Domains (1) summary
    cd03015
    Location:9 → 180
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    12730404..12733442
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005208653.3 → XP_005208710.1  peroxiredoxin-2 isoform X1

    See identical proteins and their annotated locations for XP_005208710.1

    UniProtKB/Swiss-Prot
    Q3T0L0, Q9BGI3
    UniProtKB/TrEMBL
    A0AAA9RUA3
    Related
    ENSBTAP00000075686.1, ENSBTAT00000089598.1
    Conserved Domains (1) summary
    cd03015
    Location:9 → 180
    PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9BGI3.1 GenPept UniProtKB/Swiss-Prot:Q9BGI3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.