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mtx1b metaxin 1b [ Danio rerio (zebrafish) ]

Gene ID: 286740, updated on 4-Jan-2025

Summary

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Official Symbol
mtx1bprovided by ZNC
Official Full Name
metaxin 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-021210-1
See related
Ensembl:ENSDARG00000036109 AllianceGenome:ZFIN:ZDB-GENE-021210-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
mtx1; zgc:101675
Summary
Predicted to be involved in mitochondrion organization. Predicted to act upstream of or within protein transport. Predicted to be located in mitochondrial outer membrane. Predicted to be part of SAM complex. Predicted to be active in cytoplasm. Is expressed in alar plate midbrain region; immature eye; myotome; and optic tectum. Orthologous to human MTX1 (metaxin 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See mtx1b in Genome Data Viewer
Location:
chromosome: 19
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (24447271..24484762, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (24864369..24900535, complement)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene si:dkey-81h8.1 Neighboring gene thrombospondin 3b Neighboring gene thioredoxin interacting protein a Neighboring gene RNA polymerase III subunit GL a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The zebrafish metaxin 3 gene (mtx3): cDNA and protein structure, and comparison to zebrafish metaxins 1 and 2. Adolph KW. Gene, 2004 Apr 14. PMID 15087125
  2. Phylogenomic analysis of vertebrate thrombospondins reveals fish-specific paralogues, ancestral gene relationships and a tetrapod innovation. McKenzie P, et al. BMC Evol Biol, 2006 Apr 18. PMID 16620379, Free PMC Article
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC101675

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in mitochondrion organization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within mitochondrion organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of SAM complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SAM complex IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
metaxin-1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007280.1 → NP_001007281.1  metaxin-1b

    See identical proteins and their annotated locations for NP_001007281.1

    Status: PROVISIONAL

    Source sequence(s)
    BC085411
    UniProtKB/TrEMBL
    Q5RKQ2
    Related
    ENSDARP00000052421.2, ENSDART00000052422.3
    Conserved Domains (2) summary
    cd03212
    Location:106 → 242
    GST_C_Metaxin1_3; C-terminal, alpha helical domain of Metaxin 1, Metaxin 3, and similar proteins
    cd03078
    Location:5 → 78
    GST_N_Metaxin1_like; GST_N family, Metaxin subfamily, Metaxin 1-like proteins; composed of metaxins 1 and 3, and similar proteins including Tom37 from fungi. Mammalian metaxin (or metaxin 1) and the fungal protein Tom37 are components of preprotein import complexes of the ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    24447271..24484762 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021467980.2 → XP_021323655.1  metaxin-1b isoform X1

    UniProtKB/TrEMBL
    A0A8M9PR98
    Conserved Domains (2) summary
    cd03212
    Location:106 → 242
    GST_C_Metaxin1_3; C-terminal, alpha helical domain of Metaxin 1, Metaxin 3, and similar proteins
    pfam10568
    Location:7 → 144
    Tom37; Outer mitochondrial membrane transport complex protein
Nucleotide Protein
Heading Accession and Version

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