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RPGRIP1 RPGR interacting protein 1 [ Bos taurus (domestic cattle) ]

Gene ID: 282656, updated on 27-Dec-2024

Summary

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Official Symbol
RPGRIP1provided by VGNC
Official Full Name
RPGR interacting protein 1provided by VGNC
Primary source
VGNC:VGNC:34104
See related
BGD:BT10455; Ensembl:ENSBTAG00000004694
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See RPGRIP1 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (25807379..25869097, complement)

Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene chromodomain helicase DNA binding protein 8 Neighboring gene uncharacterized LOC104973099 Neighboring gene small nucleolar RNA U6-53/MBII-28 Neighboring gene SPT16 homolog, facilitates chromatin remodeling subunit Neighboring gene histone H2B type 1-L-like Neighboring gene heterogeneous nuclear ribonucleoprotein C Neighboring gene olfactory receptor family 5 subfamily AU member 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. The retinitis pigmentosa GTPase regulator (RPGR) interacts with novel transport-like proteins in the outer segments of rod photoreceptors. Roepman R, et al. Hum Mol Genet, 2000 Sep 1. PMID 10958648
  2. Interaction of nephrocystin-4 and RPGRIP1 is disrupted by nephronophthisis or Leber congenital amaurosis-associated mutations. Roepman R, et al. Proc Natl Acad Sci U S A, 2005 Dec 20. PMID 16339905, Free PMC Article
  3. Species-specific subcellular localization of RPGR and RPGRIP isoforms: implications for the phenotypic variability of congenital retinopathies among species. Mavlyutov TA, et al. Hum Mol Genet, 2002 Aug 1. PMID 12140192
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. RPGR and RPGRIP isoforms are distributed and co-localized at restricted foci throughout the outer segments of human and bovine, but not mice rod photoreceptors.
    Title: Species-specific subcellular localization of RPGR and RPGRIP isoforms: implications for the phenotypic variability of congenital retinopathies among species.
  2. RPGRIP1 and nephrocystin-4 interact strongly in vitro and in vivo, and that they colocalize in the retina
    Title: Interaction of nephrocystin-4 and RPGRIP1 is disrupted by nephronophthisis or Leber congenital amaurosis-associated mutations.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables thromboxane A2 receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in non-motile cilium assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in retinal rod cell development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in photoreceptor connecting cilium IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1
Names
retinitis pigmentosa GTPase regulator interacting protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001434915.1 → NP_001421844.1  X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    NKLS02000010

  2. NM_001434916.1 → NP_001421845.1  X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    NKLS02000010

  3. NM_001434917.1 → NP_001421846.1  X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 isoform 4

    Status: VALIDATED

    Source sequence(s)
    NKLS02000010

  4. NM_181034.3 → NP_851377.2  X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    NKLS02000010
    Related
    ENSBTAP00000091308.1, ENSBTAT00000132599.1

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    25807379..25869097 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9GLM3.1 GenPept UniProtKB/Swiss-Prot:Q9GLM3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials