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PROCR protein C receptor [ Bos taurus (domestic cattle) ]

Gene ID: 282005, updated on 27-Dec-2024

Summary

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Official Symbol
PROCRprovided by VGNC
Official Full Name
protein C receptorprovided by VGNC
Primary source
VGNC:VGNC:33359
See related
BGD:BT13648; Ensembl:ENSBTAG00000008291
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
EPCR
Orthologs
human mouse all
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Genomic context

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See PROCR in Genome Data Viewer
Location:
chromosome: 13
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 13 NC_037340.1 (64441610..64449124)

Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene transient receptor potential cation channel subfamily C member 4 associated protein Neighboring gene ER degradation enhancing alpha-mannosidase like protein 2 Neighboring gene matrix metallopeptidase 24 Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene MMP24 opposite strand

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. Molecular cloning and expression of murine and bovine endothelial cell protein C/activated protein C receptor (EPCR). The structural and functional conservation in human, bovine, and murine EPCR. Fukudome K, et al. J Biol Chem, 1995 Mar 10. PMID 7890676
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of coagulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
endothelial protein C receptor
Names
APC receptor
activated protein C receptor
endothelial cell protein C receptor
endothelial cell protein C/activated protein C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174437.1 → NP_776862.1  endothelial protein C receptor precursor

    See identical proteins and their annotated locations for NP_776862.1

    Status: PROVISIONAL

    Source sequence(s)
    L39065
    UniProtKB/Swiss-Prot
    Q1LZD2, Q28105
    UniProtKB/TrEMBL
    A0AAF6YSI3
    Related
    ENSBTAP00000010911.4, ENSBTAT00000010911.5
    Conserved Domains (1) summary
    cl08246
    Location:22 → 192
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037340.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    64441610..64449124
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059892393.1 → XP_059748376.1  endothelial protein C receptor isoform X1

    UniProtKB/TrEMBL
    A0AAA9RUZ5, A0AAF6YSI3

  2. XM_059892394.1 → XP_059748377.1  endothelial protein C receptor isoform X1

    UniProtKB/TrEMBL
    A0AAA9RUZ5, A0AAF6YSI3
    Related
    ENSBTAP00000074792.1, ENSBTAT00000124883.1
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q28105.1 GenPept UniProtKB/Swiss-Prot:Q28105

Gene LinkOut

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