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AVPR2 arginine vasopressin receptor 2 [ Bos taurus (domestic cattle) ]

Gene ID: 281642, updated on 30-Jan-2025

Summary

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Official Symbol
AVPR2provided by VGNC
Official Full Name
arginine vasopressin receptor 2provided by VGNC
Primary source
VGNC:VGNC:26360
See related
EnsemblRapid:ENSBTAG00070032868
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See AVPR2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (37122575..37125020)

Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein eL21-like Neighboring gene L1 cell adhesion molecule Neighboring gene Rho GTPase activating protein 4 Neighboring gene N-alpha-acetyltransferase 10, NatA catalytic subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. Direct identification of an extracellular agonist binding site in the renal V2 vasopressin receptor. Kojro E, et al. Biochemistry, 1993 Dec 14. PMID 8257689
  2. An extracellular residue determines the agonist specificity of V2 vasopressin receptors. Ufer E, et al. FEBS Lett, 1995 Mar 27. PMID 7698346
  3. Involvement of the V2 vasopressin receptor in adaptation to limited water supply. Böselt I, et al. PLoS One, 2009. PMID 19440390, Free PMC Article
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables peptide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables vasopressin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to hormone stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of vasoconstriction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of systemic arterial blood pressure by vasopressin IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
vasopressin V2 receptor
Names
AVPR V2
V2R
antidiuretic hormone receptor
arginine vasopressin receptor 2 (nephrogenic diabetes insipidus)
renal-type arginine vasopressin receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174246.2 → NP_776671.1  vasopressin V2 receptor

    See identical proteins and their annotated locations for NP_776671.1

    Status: PROVISIONAL

    Source sequence(s)
    X83741
    UniProtKB/Swiss-Prot
    P48044
    UniProtKB/TrEMBL
    C5HF06
    Conserved Domains (1) summary
    pfam00001
    Location:55 → 324
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    37122575..37125020
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005227662.5 → XP_005227719.1  vasopressin V2 receptor isoform X1

    UniProtKB/TrEMBL
    A0AAF6ZQP5
    Related
    ENSBTAP00070045222.1, ENSBTAT00070074228.1
    Conserved Domains (2) summary
    pfam00001
    Location:44 → 313
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam12444
    Location:219 → 256
    Sox_N; Sox developmental protein N terminal
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P48044.1 GenPept UniProtKB/Swiss-Prot:P48044

Gene LinkOut

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