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CHAD chondroadherin [ Bos taurus (domestic cattle) ]

Gene ID: 281069, updated on 27-Dec-2024

Summary

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Official Symbol
CHADprovided by VGNC
Official Full Name
chondroadherinprovided by VGNC
Primary source
VGNC:VGNC:27264
See related
BGD:BT10713; Ensembl:ENSBTAG00000021302
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See CHAD in Genome Data Viewer
Location:
chromosome: 19
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (36246948..36259890)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene radical S-adenosyl methionine domain containing 1 Neighboring gene microRNA mir-584-2 Neighboring gene acyl-CoA synthetase family member 2 Neighboring gene uncharacterized LOC104975061 Neighboring gene leucine rich repeat containing 59

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. The structure of a 38-kDa leucine-rich protein (chondroadherin) isolated from bovine cartilage. Neame PJ, et al. J Biol Chem, 1994 Aug 26. PMID 8063792
  2. Isolation and molecular cloning of a novel bone phosphoprotein related in sequence to the cystatin family of thiol protease inhibitors. Hu B, et al. J Biol Chem, 1995 Jan 6. PMID 7814406
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
chondroadherin
Names
38 kDa bone protein
cartilage leucine-rich protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174019.2 → NP_776444.1  chondroadherin precursor

    See identical proteins and their annotated locations for NP_776444.1

    Status: PROVISIONAL

    Source sequence(s)
    U08018
    UniProtKB/Swiss-Prot
    Q27972
    UniProtKB/TrEMBL
    C6KE16
    Related
    ENSBTAP00000028386.3, ENSBTAT00000028386.4
    Conserved Domains (7) summary
    smart00082
    Location:302 → 349
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:126 → 302
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:295 → 306
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:55 → 78
    LRR_RI; leucine-rich repeat [structural motif]
    pfam01462
    Location:25 → 51
    LRRNT; Leucine rich repeat N-terminal domain
    pfam12799
    Location:101 → 141
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:77 → 137
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    36246948..36259890
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005220480.5 → XP_005220537.1  chondroadherin isoform X1

    See identical proteins and their annotated locations for XP_005220537.1

    UniProtKB/TrEMBL
    C6KE16
    Conserved Domains (6) summary
    smart00082
    Location:302 → 349
    LRRCT; Leucine rich repeat C-terminal domain
    COG4886
    Location:108 → 303
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00031
    Location:295 → 306
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:55 → 78
    LRR_RI; leucine-rich repeat [structural motif]
    pfam01462
    Location:25 → 51
    LRRNT; Leucine rich repeat N-terminal domain
    pfam13855
    Location:77 → 137
    LRR_8; Leucine rich repeat
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q27972.1 GenPept UniProtKB/Swiss-Prot:Q27972

Gene LinkOut

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Molecular Biology Databases
Research Materials