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F3 coagulation factor III, tissue factor [ Bos taurus (domestic cattle) ]

Gene ID: 280686, updated on 1-Jan-2025

Summary

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Official Symbol
F3provided by VGNC
Official Full Name
coagulation factor III, tissue factorprovided by VGNC
Primary source
VGNC:VGNC:28687
See related
BGD:BT23303; Ensembl:ENSBTAG00000007101
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
TF
Annotation information
Note: GeneIDs 280686 and 100849695 are annotated independently on Btau_4.6.1, but may be redundant loci. [17 Jun 2014]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (48954585..48965468)

Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112445986 Neighboring gene uncharacterized LOC132344873 Neighboring gene U6 spliceosomal RNA Neighboring gene ATP binding cassette subfamily D member 3 Neighboring gene uncharacterized LOC132344875 Neighboring gene uncharacterized LOC132344874

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. cDNA and amino acid sequences of bovine tissue factor. Takayenoki Y, et al. Biochem Biophys Res Commun, 1991 Dec 31. PMID 1764065
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in blood coagulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tissue factor
Names
coagulation factor III (thromboplastin, tissue factor)
thromboplastin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173878.2 → NP_776303.1  tissue factor precursor

    See identical proteins and their annotated locations for NP_776303.1

    Status: PROVISIONAL

    Source sequence(s)
    S74147
    UniProtKB/Swiss-Prot
    P30931, Q08DD5
    UniProtKB/TrEMBL
    A0AAA9TR18
    Related
    ENSBTAP00000009341.3, ENSBTAT00000009341.5
    Conserved Domains (2) summary
    pfam01108
    Location:33 → 118
    Tissue_fac; Tissue factor
    pfam09294
    Location:135 → 242
    Interfer-bind; Interferon-alpha/beta receptor, fibronectin type III

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    48954585..48965468
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P30931.1 GenPept UniProtKB/Swiss-Prot:P30931

Gene LinkOut

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