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squ squash [ Drosophila melanogaster (fruit fly) ]

Gene ID: 2768920, updated on 9-Dec-2024

Summary

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Official Symbol
squprovided by FlyBase
Official Full Name
squashprovided by FlyBase
Primary source
FLYBASE:FBgn0267347
Locus tag
Dmel_CG4711
See related
AllianceGenome:FB:FBgn0267347
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
atg; CG4711; Dmel\CG4711; mat(2)cell-A; mat(2)cellHK35; SQU
Summary
Involved in regulatory ncRNA-mediated gene silencing. Located in P granule. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See squ in Genome Data Viewer
Location:
36A10-36A10; 2-52 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16680054..16681653)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16680054..16681653)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Transient receptor potential cation channel gamma Neighboring gene mir-2497 stem loop Neighboring gene hermaphrodite Neighboring gene uncharacterized protein Neighboring gene grapes Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44975

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Drosophila grapes gene is related to checkpoint gene chk1/rad27 and is required for late syncytial division fidelity. Fogarty P, et al. Curr Biol, 1997 Jun 1. PMID 9197245
  2. The epigenetic trans-silencing effect in Drosophila involves maternally-transmitted small RNAs whose production depends on the piRNA pathway and HP1. Todeschini AL, et al. PLoS One, 2010 Jun 14. PMID 20559422, Free PMC Article
  3. Probing the initiation and effector phases of the somatic piRNA pathway in Drosophila. Haase AD, et al. Genes Dev, 2010 Nov 15. PMID 20966049, Free PMC Article
  4. Mutations to the piRNA pathway component aubergine enhance meiotic drive of segregation distorter in Drosophila melanogaster. Gell SL, et al. Genetics, 2013 Mar. PMID 23267055, Free PMC Article
  5. Spindle-E cycling between nuage and cytoplasm is controlled by Qin and PIWI proteins. Andress A, et al. J Cell Biol, 2016 Apr 25. PMID 27091448, Free PMC Article

See all (71) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in dorsal appendage formation HMP PubMed 
involved_in oogenesis HMP PubMed 
involved_in oogenesis TAS
Traceable Author Statement
more info
 PubMed 
involved_in regulatory ncRNA-mediated gene silencing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in P granule IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
squash
Names
CG4711-PA
CG4711-PB
CG4711-PC
adjacent-to-grapes
squ-PA
squ-PB
squ-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    16680054..16681653
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_206000.4 → NP_995722.1  squash, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995722.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    L0CPT7, L0CRL5, Q7KT57

  2. NM_001273578.1 → NP_001260507.1  squash, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260507.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    L0CPT7, L0CRL5, Q7KT57

  3. NM_001259115.2 → NP_001246044.1  squash, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246044.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    L0CPT7, L0CRL5, Q7KT57
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7KT57 Q7KT57

Gene LinkOut

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