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Or46a Odorant receptor 46a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 2768728, updated on 9-Dec-2024

Summary

Official Symbol
Or46aprovided by FlyBase
Official Full Name
Odorant receptor 46aprovided by FlyBase
Primary source
FLYBASE:FBgn0026388
Locus tag
Dmel_CG33478
See related
AllianceGenome:FB:FBgn0026388
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
46a; 46b; 46F.1; AN8; AN9; CG17848; CG17849; CG33478; DmelOR46a; Dmel\CG33478; dor19; DOR19; DOR20; DOR46F.1; DOR46F.2; Or19; OR46a; Or46aa; Or46aA; Or46aB; Or46b; Or46B; Or46F.1; Or46F.2
Summary
Enables olfactory receptor activity. Involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in dendrite membrane. Predicted to be active in plasma membrane. Is expressed in adult labial nerve; adult olfactory antennal lobe glomerulus; maxillary palp; maxillary palp basiconic sensillum pb2; and olfactory receptor neurons. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Or46a in Genome Data Viewer
Location:
46F2-46F2; 2-62 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10139264..10142074)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6026769..6029579)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Copper chaperone for superoxide dismutase Neighboring gene gemini Neighboring gene antisense RNA:CR43467 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45133 Neighboring gene KCNQ potassium channel

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables odorant binding IEA
Inferred from Electronic Annotation
more info
 
enables odorant binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables olfactory receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables olfactory receptor activity NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in dendrite membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
PubMed 

General protein information

Preferred Names
odorant receptor 46a
Names
CG33478-PA
CG33478-PB
Or46a-PA
Or46a-PB
odorant receptor 46b
olfactory receptor 46F.1
olfactory receptor 46F.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    10139264..10142074
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_206072.2NP_995794.1  odorant receptor 46a, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995794.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P81919, Q9U6X9, Q9V5H3
    Conserved Domains (1) summary
    pfam02949
    Location:63370
    7tm_6; 7tm Odorant receptor
  2. NM_206071.2NP_995793.1  odorant receptor 46a, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995793.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P81920, Q9V3N2
    Conserved Domains (1) summary
    pfam02949
    Location:62373
    7tm_6; 7tm Odorant receptor