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CheB42b Chemosensory protein B 42b [ Drosophila melanogaster (fruit fly) ]

Gene ID: 2768717, updated on 4-Jan-2025

Summary

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Official Symbol
CheB42bprovided by FlyBase
Official Full Name
Chemosensory protein B 42bprovided by FlyBase
Primary source
FLYBASE:FBgn0066293
Locus tag
Dmel_CG33351
See related
AllianceGenome:FB:FBgn0066293
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG15241; CG33351; CheB42; Dmel\CG33351
Summary
Predicted to enable lipid binding activity. Involved in detection of pheromone. Predicted to be located in extracellular space. Is expressed in prothoracic leg; third segment of antenna; and wing. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CheB42b in Genome Data Viewer
Location:
42E1-42E1; 2-55 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (6943096..6943995, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (2830601..2831500, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene missing-in-metastasis Neighboring gene transfer RNA:Lysine-CTT 1-6 Neighboring gene transfer RNA:Lysine-CTT 1-7 Neighboring gene Chemosensory protein B 42c

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Drosophila protein family implicated in pheromone perception is related to Tay-Sachs GM2-activator protein. Starostina E, et al. J Biol Chem, 2009 Jan 2. PMID 18952610, Free PMC Article
  2. Who is he and what is he to you? Recognition in Drosophila melanogaster. Billeter JC, et al. Curr Opin Neurobiol, 2013 Feb. PMID 23010098
  3. Novel genes expressed in subsets of chemosensory sensilla on the front legs of male Drosophila melanogaster. Xu A, et al. Cell Tissue Res, 2002 Mar. PMID 11904775
  4. A Drosophila DEG/ENaC channel subunit is required for male response to female pheromones. Lin H, et al. Proc Natl Acad Sci U S A, 2005 Sep 6. PMID 16129837, Free PMC Article
  5. Identification of genetic modifiers of TDP-43 neurotoxicity in Drosophila. Zhan L, et al. PLoS One, 2013. PMID 23468938, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables lipid binding ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of pheromone IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in sensory perception of chemical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
 PubMed 
located_in extracellular space ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
chemosensory protein B 42b
Names
CG33351-PA
CheB42b-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    6943096..6943995 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_206041.2 → NP_995763.1  chemosensory protein B 42b [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995763.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z6S1, E0R925
    Conserved Domains (1) summary
    smart00675
    Location:17 → 180
    DM11; Domains in hypothetical proteins in Drosophila including 2 in CG15241 and CG9329
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1Z6S1 A1Z6S1

Gene LinkOut

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