U.S. flag

An official website of the United States government

adra2da adrenergic, alpha-2D-, receptor a [ Danio rerio (zebrafish) ]

Gene ID: 266754, updated on 9-Dec-2024

Summary

Official Symbol
adra2daprovided by ZNC
Official Full Name
adrenergic, alpha-2D-, receptor aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-021010-4
See related
Ensembl:ENSDARG00000091277 AllianceGenome:ZFIN:ZDB-GENE-021010-4
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Enables alpha2-adrenergic receptor activity. Involved in adenylate cyclase-inhibiting adrenergic receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in brain; cerebellum; musculature system; optic tectum; and ovary. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See adra2da in Genome Data Viewer
Location:
chromosome: 14
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (790166..792959)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (771902..774695)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene klotho beta Neighboring gene tripartite motif containing 35-27 Neighboring gene solute carrier family 34 member 1a Neighboring gene si:ch73-302a4.4

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC158196

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables G protein-coupled receptor activity  
enables adrenergic receptor activity  
enables alpha2-adrenergic receptor activity  
enables alpha2-adrenergic receptor activity PubMed 
enables alpha2-adrenergic receptor activity  
enables alpha2-adrenergic receptor activity PubMed 
enables epinephrine binding  
Component Evidence Code Pubs
located_in membrane  
is_active_in plasma membrane  
located_in plasma membrane PubMed 
located_in plasma membrane  
located_in plasma membrane PubMed 

General protein information

Preferred Names
alpha-2Da adrenergic receptor
Names
alpha(2Da)AR
alpha-2Da adrenoceptor
alpha-2Da adrenoreceptor

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_194364.2 → NP_919345.2  alpha-2Da adrenergic receptor

    See identical proteins and their annotated locations for NP_919345.2

    Status: PROVISIONAL

    Source sequence(s)
    BC129157
    UniProtKB/Swiss-Prot
    Q8JG70
    UniProtKB/TrEMBL
    A0A8M1PCE6, A1L1P0
    Related
    ENSDARP00000105653.1, ENSDART00000123912.3
    Conserved Domains (2) summary
    pfam00001
    Location:47 → 386
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:45 → 183
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    790166..792959
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
External link. Please review our privacy policy.