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Defb36 defensin beta 36 [ Mus musculus (house mouse) ]

Gene ID: 266620, updated on 27-Nov-2024

Summary

Official Symbol
Defb36provided by MGI
Official Full Name
defensin beta 36provided by MGI
Primary source
MGI:MGI:2385956
See related
Ensembl:ENSMUSG00000044863 AllianceGenome:MGI:2385956
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
BD-36; mBD-36; Defb123
Summary
Predicted to be involved in defense response to bacterium and innate immune response. Predicted to be located in extracellular region. Orthologous to human DEFB123 (defensin beta 123). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward testis adult (RPKM 34.7) See more
Orthologs
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Genomic context

See Defb36 in Genome Data Viewer
Location:
2 H1; 2 75.41 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (152446247..152454649)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (152604327..152612729)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene defensin beta 19 Neighboring gene defensin beta 45 Neighboring gene protein kish-A pseudogene Neighboring gene predicted gene, 31618 Neighboring gene defensin beta 25 Neighboring gene rad and gem related GTP binding protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in defense response to bacterium IEA
Inferred from Electronic Annotation
more info
 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
beta-defensin 36
Names
defensin beta 123

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037247.4NP_001032324.1  beta-defensin 36 precursor

    See identical proteins and their annotated locations for NP_001032324.1

    Status: VALIDATED

    Source sequence(s)
    BX631384, DQ012042
    Consensus CDS
    CCDS38279.1
    UniProtKB/Swiss-Prot
    A3KGR4, Q3V491, Q8K3U4
    Related
    ENSMUSP00000059665.6, ENSMUST00000058086.6
    Conserved Domains (1) summary
    pfam13841
    Location:2453
    Defensin_beta_2; Beta defensin

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    152446247..152454649
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)