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CG31683 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 261623, updated on 9-Dec-2024

Summary

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Official Symbol
CG31683provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0051683
Locus tag
Dmel_CG31683
See related
AllianceGenome:FB:FBgn0051683
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GH02384; Dmel\CG31683
Summary
Enables serine hydrolase activity. Predicted to be involved in lipid metabolic process. Is expressed in adult fat body. Human ortholog(s) of this gene implicated in Norum disease and arteriosclerosis. Orthologous to several human genes including PLA2G15 (phospholipase A2 group XV). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG31683 in Genome Data Viewer
Location:
38C7-38C7; 2-54 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (20447734..20449964, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (20447734..20449964, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43607 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cell division cycle 23 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A field-based quantitative analysis of sublethal effects of air pollution on pollinators. Thimmegowda GG, et al. Proc Natl Acad Sci U S A, 2020 Aug 25. PMID 32778582, Free PMC Article
  2. RNAi screening of Drosophila (Sophophora) melanogaster S2 cells for ricin sensitivity and resistance. Pawar V, et al. J Biomol Screen, 2011 Apr. PMID 21364088, Free PMC Article
  3. Exploring the correlation between deltamethrin stress and Keap1-Nrf2-ARE pathway from Drosophila melanogaster RNASeq data. Liu Y, et al. Genomics, 2020 Mar. PMID 31376529
  4. Fat body-specific reduction of CTPS alleviates HFD-induced obesity. Liu J, et al. Elife, 2023 Sep 11. PMID 37695169, Free PMC Article
  5. Novel regulators of planar cell polarity: a genetic analysis in Drosophila. Weber U, et al. Genetics, 2012 May. PMID 22391484, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables O-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine hydrolase activity HDA PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG31683-PA
CG31683-PB
sterol o-acyltransferase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    20447734..20449964 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_165330.3 → NP_724265.2  uncharacterized protein Dmel_CG31683, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724265.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    C3KGK6, Q8INV2, Q9Y168
    Related
    FBpp0080897
    Conserved Domains (1) summary
    cl21494
    Location:81 → 405
    Abhydrolase; alpha/beta hydrolases

  2. NM_001273697.1 → NP_001260626.1  uncharacterized protein Dmel_CG31683, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260626.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C3KGK6, Q8INV2, Q9Y168
    Conserved Domains (1) summary
    cl21494
    Location:81 → 405
    Abhydrolase; alpha/beta hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9Y168 Q9Y168

Gene LinkOut

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