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tbx-7 Putative T-box protein 7 [ Caenorhabditis elegans ]

Gene ID: 260030, updated on 9-Dec-2024

Summary

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Official Symbol
tbx-7
Official Full Name
Putative T-box protein 7
Primary source
WormBase:WBGene00006544
Locus tag
CELE_ZK328.8
See related
AllianceGenome:WB:WBGene00006544
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See tbx-7 in Genome Data Viewer
Location:
chromosome: III
Exon count:
6
Sequence:
Chromosome: III; NC_003281.10 (6024958..6028532, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Tr-type G domain-containing protein Neighboring gene Nuclear pore complex protein Nup98 Neighboring gene ncRNA Neighboring gene Ubiquitin carboxyl-terminal hydrolase cyk-3 Neighboring gene ncRNA Neighboring gene putative F-box protein ZK328.6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Conservation of the T-box gene family from Mus musculus to Caenorhabditis elegans. Agulnik SI, et al. Genomics, 1995 Jan 1. PMID 7774921
  2. Three novel T-box genes in Caenorhabditis elegans. Agulnik SI, et al. Genome, 1997 Aug. PMID 9276934
  3. Role of T-box gene tbx-2 for anterior foregut muscle development in C. elegans. Smith PA, et al. Dev Biol, 2007 Feb 1. PMID 17005176, Free PMC Article
  4. C. elegans molting requires rhythmic accumulation of the Grainyhead/LSF transcription factor GRH-1. Meeuse MWM, et al. EMBO J, 2023 Feb 15. PMID 36688410, Free PMC Article
  5. A regulatory network of T-box genes and the even-skipped homologue vab-7 controls patterning and morphogenesis in C. elegans. Pocock R, et al. Development, 2004 May. PMID 15102704

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in cell fate specification IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in developmental process IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in chromatin IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
part_of transcription regulator complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
Putative T-box protein 7
NP_001368539.1
  • Confirmed by transcript evidence
NP_001368540.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    6024958..6028532 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001379739.1 → NP_001368539.1  Putative T-box protein 7 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (1) summary
    pfam00907
    Location:30 → 209
    T-box

  2. NM_001379738.1 → NP_001368540.1  Putative T-box protein 7 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A0K3ARF9, A0A0K3AUZ0, Q23467, Q95PX3
    Conserved Domains (1) summary
    pfam00907
    Location:66 → 245
    T-box
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q95PX3.2

Gene LinkOut

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