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Or4a15 olfactory receptor family 4 subfamily A member 15 [ Mus musculus (house mouse) ]

Gene ID: 258975, updated on 27-Nov-2024

Summary

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Official Symbol
Or4a15provided by MGI
Official Full Name
olfactory receptor family 4 subfamily A member 15provided by MGI
Primary source
MGI:MGI:3031068
See related
Ensembl:ENSMUSG00000075090 AllianceGenome:MGI:3031068
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MOR231-2; Olfr1234
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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Genomic context

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See Or4a15 in Genome Data Viewer
Location:
2 E1; 2 50.03 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (89192827..89203990, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (89362483..89373646, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily C member 124 Neighboring gene olfactory receptor family 4 subfamily C member 125 Neighboring gene olfactory receptor 1235, pseudogene 1 Neighboring gene olfactory receptor GA_x5J8B7W62NC-653162-652995

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sensitivity-dependent hierarchical receptor codes for odors. Hamana H, et al. Chem Senses, 2003 Feb. PMID 12588732
  2. Supersensitive detection and discrimination of enantiomers by dorsal olfactory receptors: evidence for hierarchical odour coding. Sato T, et al. Sci Rep, 2015 Sep 11. PMID 26361056, Free PMC Article
  3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
  4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
  5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
olfactory receptor 1234
Names
GA_x6K02T2Q125-50805620-50804676
olfactory receptor MOR231-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146973.2 → NP_667184.2  olfactory receptor 1234

    See identical proteins and their annotated locations for NP_667184.2

    Status: VALIDATED

    Source sequence(s)
    AL929555
    Consensus CDS
    CCDS16377.1
    UniProtKB/TrEMBL
    A2AVK5, Q8VGN1
    Related
    ENSMUSP00000097371.2, ENSMUST00000099783.2
    Conserved Domains (2) summary
    pfam00001
    Location:39 → 285
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:29 → 303
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    89192827..89203990 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017318612.1 → XP_017174101.1  olfactory receptor 1234 isoform X1

    UniProtKB/TrEMBL
    Q8VGN1
    Conserved Domains (1) summary
    cd15939
    Location:36 → 302
    7tmA_OR4A-like; olfactory receptor 4A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein Strain
Heading Accession and Version

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