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Or4p21 olfactory receptor family 4 subfamily P member 21 [ Mus musculus (house mouse) ]

Gene ID: 258167, updated on 9-Dec-2024

Summary

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Official Symbol
Or4p21provided by MGI
Official Full Name
olfactory receptor family 4 subfamily P member 21provided by MGI
Primary source
MGI:MGI:3031370
See related
Ensembl:ENSMUSG00000090097 AllianceGenome:MGI:3031370
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm13757; Olfr1182; MOR225-7P; MOR225-8P; Olfr1536-ps1
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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Genomic context

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See Or4p21 in Genome Data Viewer
Location:
2 D; 2 49.98 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (88276363..88279465, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (88446019..88449121, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily P member 19 Neighboring gene olfactory receptor family 4 subfamily P member 20 Neighboring gene STARR-seq mESC enhancer starr_05064 Neighboring gene olfactory receptor family 4 subfamily C member 31 Neighboring gene STARR-seq mESC enhancer starr_05065 Neighboring gene olfactory receptor family 4 subfamily P member 22

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of potential regulatory motifs in odorant receptor genes by analysis of promoter sequences. Michaloski JS, et al. Genome Res, 2006 Sep. PMID 16902085, Free PMC Article
  2. Odorant and vomeronasal receptor genes in two mouse genome assemblies. Zhang X, et al. Genomics, 2004 May. PMID 15081110
  3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
  4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
  5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
olfactory receptor 1182
Names
GA_x6K02T2Q125-49934557-49933640
MOR225-16_p
olfactory receptor 1536, pseudogene 1
olfactory receptor MOR225-7P
olfactory receptor MOR225-8P

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011535.2 → NP_001011535.1  olfactory receptor 1182

    See identical proteins and their annotated locations for NP_001011535.1

    Status: VALIDATED

    Source sequence(s)
    AL928912, DR065631
    Consensus CDS
    CCDS16336.1
    UniProtKB/TrEMBL
    Q7TR17
    Related
    ENSMUSP00000136580.2, ENSMUST00000179450.9
    Conserved Domains (2) summary
    pfam00001
    Location:39 → 285
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:29 → 302
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    88276363..88279465 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_001948.1: Suppressed sequence

    Description
    NG_001948.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
Nucleotide Protein Strain
Heading Accession and Version

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