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rad9 checkpoint clamp complex protein Rad9 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543544, updated on 18-Sep-2024

Summary

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Official Symbol
rad9
Official Full Name
checkpoint clamp complex protein Rad9
Primary source
PomBase:SPAC664.07c
Locus tag
SPOM_SPAC664.07C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See rad9 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003424.3 (1713920..1715716, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ribosome biogenesis protein rlp7 Neighboring gene traub family ribosome biogenesis protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The phosphorylation network for efficient activation of the DNA replication checkpoint in fission yeast. Yue M, et al. J Biol Chem, 2011 Jul 1. PMID 21561865, Free PMC Article
  2. Extragenic suppressors of Schizosaccharomyces pombe rad9 mutations uncouple radioresistance and hydroxyurea sensitivity from cell cycle checkpoint control. Lieberman HB. Genetics, 1995 Sep. PMID 8536960, Free PMC Article
  3. Fission yeast rad12+ regulates cell cycle checkpoint control and is homologous to the Bloom's syndrome disease gene. Davey S, et al. Mol Cell Biol, 1998 May. PMID 9566891, Free PMC Article
  4. Nuclear factories for signalling and repairing DNA double strand breaks in living fission yeast. Meister P, et al. Nucleic Acids Res, 2003 Sep 1. PMID 12930957, Free PMC Article
  5. Fission yeast strains with circular chromosomes require the 9-1-1 checkpoint complex for the viability in response to the anti-cancer drug 5-fluorodeoxyuridine. Shamim HM, et al. PLoS One, 2017. PMID 29121084, Free PMC Article

See all (51) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase activator activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables signaling adaptor activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA repair IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in DNA replication checkpoint signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cellular response to ionizing radiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic DNA damage checkpoint signaling EXP
Inferred from Experiment
more info
 PubMed 
involved_in mitotic DNA replication checkpoint signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitotic intra-S DNA damage checkpoint signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic intra-S DNA damage checkpoint signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in telomere maintenance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of checkpoint clamp complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of checkpoint clamp complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in chromosome, telomeric repeat region IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in site of double-strand break IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
checkpoint clamp complex protein Rad9

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1713920..1715716 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018888.3 → NP_593455.1  checkpoint clamp complex protein Rad9 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593455.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P26306, Q10455
    UniProtKB/TrEMBL
    A6YRR9
    Conserved Domains (2) summary
    pfam04139
    Location:13 → 300
    Rad9; Rad9
    cl24017
    Location:9 → 301
    PCNA; Proliferating Cell Nuclear Antigen (PCNA) domain found in eukaryotes and archaea. These polymerase processivity factors play a role in DNA replication and repair. PCNA encircles duplex DNA in its central cavity, providing a DNA-bound platform for the ...
Nucleotide Protein
Heading Accession and Version

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