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ubc13 ubiquitin-conjugating enzyme Ubc13 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542925, updated on 18-Sep-2024

Summary

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Official Symbol
ubc13
Official Full Name
ubiquitin-conjugating enzyme Ubc13
Primary source
PomBase:SPAC11E3.04c
Locus tag
SPOM_SPAC11E3.04C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
spu13; sst5
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Genomic context

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See ubc13 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003424.3 (5287180..5288094, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene microtubule-site clamp monopolin complex subunit Csm1/Pcs1 Neighboring gene ncRNA Neighboring gene SEA complex subunit Sea3 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural and functional conservation of error-free DNA postreplication repair in Schizosaccharomyces pombe. Brown M, et al. DNA Repair (Amst), 2002 Nov 3. PMID 12531016
  2. Role of Nse1 Subunit of SMC5/6 Complex as a Ubiquitin Ligase. Kolesar P, et al. Cells, 2022 Jan 4. PMID 35011726, Free PMC Article
  3. Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast. Gatti L, et al. BMC Genomics, 2011 Jan 19. PMID 21247416, Free PMC Article
  4. Histone H3G34R mutation causes replication stress, homologous recombination defects and genomic instability in S. pombe. Yadav RK, et al. Elife, 2017 Jul 18. PMID 28718400, Free PMC Article
  5. Isolation of suppressor mutants of phosphatidylinositol 3-phosphate 5-kinase deficient cells in Schizosaccharomyces pombe. Onishi M, et al. Biosci Biotechnol Biochem, 2003 Aug. PMID 12951513

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show that ubc13 mutants exhibiting hypersensitivity to cisplatin.
    Title: Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables ubiquitin conjugating enzyme activity EXP
Inferred from Experiment
more info
 PubMed 
enables ubiquitin conjugating enzyme activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin conjugating enzyme activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ubiquitin protein ligase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in UV-damage excision repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cytoplasm to vacuole targeting by the NVT pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in postreplication repair IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in postreplication repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein K63-linked ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ubiquitin-conjugating enzyme Ubc13

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    5287180..5288094 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020360.3 → NP_594929.1  ubiquitin-conjugating enzyme Ubc13 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594929.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13685
    Conserved Domains (2) summary
    COG5078
    Location:4 → 148
    COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
    cl00154
    Location:1 → 148
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
Nucleotide Protein
Heading Accession and Version

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