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ade2 adenylosuccinate synthetase Ade2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542823, updated on 14-Nov-2024

Summary

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Official Symbol
ade2
Official Full Name
adenylosuccinate synthetase Ade2
Primary source
PomBase:SPAC144.03
Locus tag
SPOM_SPAC144.03
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
min10; min3
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Genomic context

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See ade2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (4654631..4656456)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene Schizosaccharomyces specific protein Neighboring gene ncRNA Neighboring gene Ino80 complex subunit Iec1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ornithine decarboxylase Spe1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of the biosynthesis of purine nucleotides in Schizosaccharomyces pombe. 3. Kinetic studies of adenylosuccinate synthetase. Nagy M, et al. Biochim Biophys Acta, 1973 May 5. PMID 4708672
  2. Two purine biosynthetic enzymes that are required for cadmium tolerance in Schizosaccharomyces pombe utilize cysteine sulfinate in vitro. Juang RH, et al. Arch Biochem Biophys, 1993 Aug 1. PMID 8346915
  3. Purine biosynthetic genes are required for cadmium tolerance in Schizosaccharomyces pombe. Speiser DM, et al. Mol Cell Biol, 1992 Dec. PMID 1448066, Free PMC Article
  4. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article
  5. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables AMP binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables GMP binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables adenylosuccinate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables adenylosuccinate synthase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in 'de novo' AMP biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in 'de novo' AMP biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in 'de novo' AMP biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in IMP metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in adenosine biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in cellular response to cadmium ion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in purine nucleotide biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
adenylosuccinate synthetase Ade2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    4654631..4656456
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020093.3 → NP_594664.1  adenylosuccinate synthetase Ade2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594664.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P79061, Q02787
    Conserved Domains (1) summary
    pfam00709
    Location:18 → 431
    Adenylsucc_synt; Adenylosuccinate synthetase
Nucleotide Protein
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