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mcp1 protein mcp1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542755, updated on 18-Sep-2024

Summary

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Official Symbol
mcp1
Official Full Name
protein mcp1
Primary source
PomBase:SPAC1687.10
Locus tag
SPOM_SPAC1687.10
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See mcp1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003424.3 (919923..922098)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ENTH/VHS domain protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene rRNA methyltransferase Spb1 Neighboring gene ncRNA Neighboring gene ubiquinone biosynthesis protein Coq4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Opposing kinesin complexes queue at plus tips to ensure microtubule catastrophe at cell ends. Meadows JC, et al. EMBO Rep, 2018 Nov. PMID 30206188, Free PMC Article
  2. Mcp1p tracks microtubule plus ends to destabilize microtubules at cell tips. Zheng F, et al. FEBS Lett, 2014 Mar 18. PMID 24530531
  3. Clr4 specificity and catalytic activity beyond H3K9 methylation. Kusevic D, et al. Biochimie, 2017 Apr. PMID 28143796
  4. Systematic localization study on novel proteins encoded by meiotically up-regulated ORFs in fission yeast. Ikebe C, et al. Biosci Biotechnol Biochem, 2011. PMID 22146723
  5. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mcp1 is an interphase-specific component of the Klp5/Klp6 complex.
    Title: Opposing kinesin complexes queue at plus tips to ensure microtubule catastrophe at cell ends.
  2. The fission yeast Schizosaccharomyces pombe protein mcp1p is a microtubule plus-end tracking protein.
    Title: Mcp1p tracks microtubule plus ends to destabilize microtubules at cell tips.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in microtubule depolymerization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasmic microtubule HDA PubMed 
is_active_in cytoplasmic microtubule plus-end IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in microtubule cytoskeleton HDA PubMed 
is_active_in mitotic spindle midzone IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protein mcp1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    919923..922098
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018524.3 → NP_593128.1  protein mcp1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593128.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94452
    Conserved Domains (1) summary
    PRK03918
    Location:2 → 234
    PRK03918; chromosome segregation protein; Provisional
Nucleotide Protein
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