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pdc102 pyruvate decarboxylase [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542602, updated on 18-Sep-2024

Summary

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Official Symbol
pdc102
Official Full Name
pyruvate decarboxylase
Primary source
PomBase:SPAC186.09
Locus tag
SPOM_SPAC186.09
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See pdc102 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (5552811..5554529)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene hydroxyacid dehydrogenase Neighboring gene ncRNA Neighboring gene L-lactate dehydrogenase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene aldo/keto reductase family protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
  2. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  3. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
  4. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360
  5. The mitochondrial genome of the fission yeast Schizosaccharomyces pombe: highly homologous introns are inserted at the same position of the otherwise less conserved cox1 genes in Schizosaccharomyces pombe and Aspergillus nidulans. Lang BF. EMBO J, 1984 Sep. PMID 6092057, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables pyruvate decarboxylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables thiamine pyrophosphate binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in aromatic amino acid family catabolic process to alcohol via Ehrlich pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in generation of precursor metabolites and energy NAS
Non-traceable Author Statement
more info
  
involved_in pyruvate metabolic process ISM
Inferred from Sequence Model
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
pyruvate decarboxylase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    5552811..5554529
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020457.1 → NP_595027.1  pyruvate decarboxylase [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595027.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9P7P6
    Conserved Domains (4) summary
    cd07038
    Location:19 → 179
    TPP_PYR_PDC_IPDC_like; Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins
    COG3961
    Location:11 → 568
    PDC1; TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate transport and metabolism, Coenzyme transport and metabolism, General function prediction only]
    cd02005
    Location:374 → 554
    TPP_PDC_IPDC; Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of ...
    pfam00205
    Location:214 → 326
    TPP_enzyme_M; Thiamine pyrophosphate enzyme, central domain
Nucleotide Protein
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