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cki3 serine/threonine protein kinase (CK1 family) Cki3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542395, updated on 18-Sep-2024

Summary

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Official Symbol
cki3
Official Full Name
serine/threonine protein kinase (CK1 family) Cki3
Primary source
PomBase:SPAC1805.05
Locus tag
SPOM_SPAC1805.05
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See cki3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003424.3 (2781152..2783133)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene nucleoporin, WD repeat Nup132 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene porphobilinogen synthase Hem2 Neighboring gene DASH complex subunit Dad2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Casein kinase 1γ acts as a molecular switch for cell polarization through phosphorylation of the polarity factor Tea1 in fission yeast. Koyano T, et al. Genes Cells, 2015 Dec. PMID 26525038, Free PMC Article
  2. Casein kinase 1γ ensures monopolar growth polarity under incomplete DNA replication downstream of Cds1 and calcineurin in fission yeast. Koyano T, et al. Mol Cell Biol, 2015 May. PMID 25691662, Free PMC Article
  3. Search for kinases related to transition of growth polarity in fission yeast. Koyano T, et al. Biosci Biotechnol Biochem, 2010. PMID 20501954
  4. Histone chaperone Asf1 plays an essential role in maintaining genomic stability in fission yeast. Tanae K, et al. PLoS One, 2012. PMID 22291963, Free PMC Article
  5. Large scale screening of genetic interaction with sgf73(+) in fission yeast. Guo Y, et al. Yi Chuan, 2014 Jul. PMID 25076038

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Study proposes that Cki3 monitors the timing of growth polarity transition from monopolar to bipolar during G2 phase onset through Tea1 phosphorylation by regulating the interaction between Tea1 and Tea4.
    Title: Casein kinase 1γ acts as a molecular switch for cell polarization through phosphorylation of the polarity factor Tea1 in fission yeast.
  2. The fission yeast Cki3 (a casein kinase 1gamma homolog) is a critical regulator to ensure persistent monopolar growth during S phase.
    Title: Casein kinase 1γ ensures monopolar growth polarity under incomplete DNA replication downstream of Cds1 and calcineurin in fission yeast.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding ISM
Inferred from Sequence Model
more info
  
enables protein kinase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of establishment of bipolar cell polarity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of protein localization to cell tip IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of endocytosis ISO
Inferred from Sequence Orthology
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in signal transduction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cell division site IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell periphery IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
serine/threonine protein kinase (CK1 family) Cki3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2781152..2783133
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019345.3 → NP_593916.1  serine/threonine protein kinase (CK1 family) Cki3 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593916.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74135
    Conserved Domains (2) summary
    COG0515
    Location:14 → 353
    SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]
    cl21453
    Location:14 → 290
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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