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scs22 VAMP/synaptobrevin-associated protein family protein [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542179, updated on 14-Nov-2024

Summary

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Official Symbol
scs22
Official Full Name
VAMP/synaptobrevin-associated protein family protein
Primary source
PomBase:SPAC17C9.12
Locus tag
SPOM_SPAC17C9.12
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See scs22 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (4477935..4479951, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene protein dhm2 Neighboring gene ncRNA Neighboring gene protein Pex19 Neighboring gene nuclear proteasome tethering factor Cut8 Neighboring gene ncRNA Neighboring gene zf-C2H2 type zinc finger protein/UBA domain protein Neighboring gene G-protein-coupled receptor Stm1 Neighboring gene TIM22 inner membrane protein import complex subunit Tim13

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ER-PM Contacts Define Actomyosin Kinetics for Proper Contractile Ring Assembly. Zhang D, et al. Curr Biol, 2016 Mar 7. PMID 26877082, Free PMC Article
  2. A UPR-Induced Soluble ER-Phagy Receptor Acts with VAPs to Confer ER Stress Resistance. Zhao D, et al. Mol Cell, 2020 Sep 17. PMID 32735772
  3. ER-PM Contacts Restrict Exocytic Sites for Polarized Morphogenesis. Ng AYE, et al. Curr Biol, 2018 Jan 8. PMID 29290560
  4. Plasma membrane tethering of the cortical ER necessitates its finely reticulated architecture. Zhang D, et al. Curr Biol, 2012 Nov 6. PMID 23041194
  5. Fission yeast Duc1 links to ER-PM contact sites and influences PM lipid composition and cytokinetic ring anchoring. Willet AH, et al. J Cell Sci, 2024 Sep 15. PMID 39239853, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables endoplasmic reticulum-autophagosome adaptor activity IPI
Inferred from Physical Interaction
more info
 PubMed 
enables endoplasmic reticulum-plasma membrane adaptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein-membrane adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in endoplasmic reticulum membrane organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum-plasma membrane tethering IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum-plasma membrane tethering IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in maintenance of ER location IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in plasma membrane organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in reticulophagy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
NOT is_active_in cell division site IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cortical endoplasmic reticulum EXP
Inferred from Experiment
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in lateral plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
VAMP/synaptobrevin-associated protein family protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    4477935..4479951 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020022.3 → NP_594594.1  VAMP/synaptobrevin-associated protein family protein [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594594.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10484
    Conserved Domains (2) summary
    COG5066
    Location:1 → 246
    SCS2; VAMP-associated protein involved in inositol metabolism [Intracellular trafficking and secretion]
    pfam00635
    Location:7 → 108
    Motile_Sperm; MSP (Major sperm protein) domain
Nucleotide Protein
Heading Accession and Version

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