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erf1 cytoplasmic translation release factor class I eRF1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542148, updated on 18-Sep-2024

Summary

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Official Symbol
erf1
Official Full Name
cytoplasmic translation release factor class I eRF1
Primary source
PomBase:SPAC1834.01
Locus tag
SPOM_SPAC1834.01
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
sup45
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Genomic context

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See erf1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (4691780..4693738)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene 6-phosphofructo-2-kinase Neighboring gene sister chromatid cohesion protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GDP-mannose transporter Vrg4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene multifunctional aromatic polypeptide Aro1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe. Kong C, et al. Mol Cell, 2004 Apr 23. PMID 15099522
  2. The stretch of C-terminal acidic amino acids of translational release factor eRF1 is a primary binding site for eRF3 of fission yeast. Ito K, et al. RNA, 1998 Aug. PMID 9701287, Free PMC Article
  3. Structure of the Dom34-Hbs1 complex and implications for no-go decay. Chen L, et al. Nat Struct Mol Biol, 2010 Oct. PMID 20890290
  4. C-terminal interaction of translational release factors eRF1 and eRF3 of fission yeast: G-domain uncoupled binding and the role of conserved amino acids. Ebihara K, et al. RNA, 1999 Jun. PMID 10376874, Free PMC Article
  5. Structural insights into eRF3 and stop codon recognition by eRF1. Cheng Z, et al. Genes Dev, 2009 May 1. PMID 19417105, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables GTPase regulator activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables sequence-specific mRNA binding EXP
Inferred from Experiment
more info
 PubMed 
enables sequence-specific mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to translation release factor activity EXP
Inferred from Experiment
more info
 PubMed 
enables translation release factor activity, codon specific IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translational termination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cytoplasmic translational termination IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of translation release factor complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of translation release factor complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of translation release factor complex IMP
Inferred from Mutant Phenotype
more info
 PubMed 
part_of translation release factor complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
cytoplasmic translation release factor class I eRF1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    4691780..4693738
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020109.3 → NP_594680.1  cytoplasmic translation release factor class I eRF1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594680.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P79063
    Conserved Domains (4) summary
    COG1503
    Location:1 → 418
    eRF1; Peptide chain release factor 1 (eRF1) [Translation, ribosomal structure and biogenesis]
    pfam03463
    Location:15 → 136
    eRF1_1; eRF1 domain 1
    pfam03464
    Location:143 → 274
    eRF1_2; eRF1 domain 2
    pfam03465
    Location:277 → 416
    eRF1_3; eRF1 domain 3
Nucleotide Protein
Heading Accession and Version

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